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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 13 September 2021 Vol. No. 10; Issue No. 492

1. Bhardwaj P, Goda JS, Pai V, Chaudhari P, Mohanty B, Pai T, Vishwakarma K, Thorat R, Wadasadawala T, Banerjee R (2021). Ultrasound augments on-demand breast tumor radiosensitization and apoptosis through a tri-responsive combinatorial delivery theranostic platform. Nanoscale.

2. Qureshi SS, Ramraj D, Chinnaswamy G, Parambil BC, Prasad M, Amin N, Ramanathan S, Khanna N, Laskar S (2021). Assessment of outcomes of elective cancer surgeries in children during coronavirus disease 2019 pandemic: Retrospective cohort study from a tertiary cancer center in India. Medicine (Baltimore). 100(35): 26752.

3. Chatterjee G, Sriram H, Ghogale S, Deshpande N, Khanka T, Girase K, Verma S, Arolkar G, Dasgupta N, Narula G, Shetty D, Dhamne C, Moulik NR, Rajpal S, Patkar NV, Banavali S, Gujral S, Subramanian PG, Tembhare PR (2021). Mimics and artefacts of measurable residual disease in a highly sensitive multicolour flow cytometry assay for B-lymphoblastic leukaemia/lymphoma: critical consideration for analysis of measurable residual disease. British Journal of Haematology.

4. Kapoor J, Mirgh SP, Agrawal N, Khushboo V, Tejwani N, Singh R, Mehta P, Bhurani D, Ahmed R (2021). High risk acute promyelocytic leukemia - An enigma for hematologists: Optimizing treatment with APML-4 Protocol. Indian Journal of Hematology and Blood Transfusion.

5. Madhugiri VS, Subeikshanan V, Dutt A, Moiyadi A, Epari S, Shetty P, Gupta T, Jalali R, Dutt AK (2021). Biomarkers of systemic inflammation in patients with glioblastoma: An analysis of correlation with tumour-related factors and survival. Neurology India. 69(4):894-901

6. Chopra S, Gupta S, Kannan S, Dora T, Engineer R, Mangaj A, Maheshwari A, Shylasree TS, Ghosh J, Paul SN, Phurailatpam R, Charnalia M, Alone M, Swamidas J, Mahantshetty U, Deodhar K, Kerkar R, Shrivastava SK (2021). Late toxicity after adjuvant conventional radiation versusi mage-guided intensity-modulated radiotherapy for cervical cancer (PARCER): A randomized controlled trial. Journal of Clinical Oncology.

Site of the Week

Orientations of Proteins in Membranes (OPM) database provides spatial arrangements of membrane proteins with respect to the hydrocarbon core of the lipid bilayer.

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Interesting Reads

G. Mahesh. Raising the bar for Indian S&T journals:Some contentions revisited. Current Science. 121(5), 2021

Legends of Science
Krishnamurthi Ganapathi Krishnamurthi Ganapathi

Krishnamurthi Ganapathi obtained his DSc degree from the University of Madras in 1941. His specialization was organic chemistry, synthetic drugs, antibiotics, biochemistry and fermentation technology. His notable contributions were the manufacturing process of sulphathiazole; synthesis of potential antimalarials and the production of paludrine; the biosynthetic pathway for penicillin production by the mould; biochemistry of Penicillium chrysogenum and some pathogenic bacteria. Dr. Ganapathi was responsible for building the Chemotherapy Department at Haffkine Institute, Mumbai and supported in setting up the Research laboratory of the Hindustan Antibiotics, Pune. He was the recipient of Sudborough Medal of Indian Institute of Science, Bangalore; Fellow of Indian Academy of Sciences and Chemical Society of UK.

Bhuban Mohan Gupta Bhuban Mohan Gupta

Bhuban Mohan Gupta obtained his PhD from the University of Pittsburgh, USA in 1950. Specialized in Virology, he isolated an antiviral agent (Double Stranded RNA) with capacity to induce interferon (pH-labile and pH-stable) and modulate immune responses in vertebrates. His research led to the discovery of a new bacteriophage called CVX-5. His study of the plaque formation of CVX-5 using the host E-coli was used to understand and analyze mammalian cell-virus interaction. Dr. Gupta was the Assistant Director, Central Drug Research Institute, Lucknow. He was a member of the Association of Microbiologists. Dr. Gupta was conferred with Indian Chemical Manufacturers Association Lecture in 1971 and Vyas Memorial Award Lecture in 1978.

Do You Know?

In 2005, The International HapMap Project set out to develop a haplotype map (HapMap) of the human genome that describes the common patterns of human DNA sequence variation.

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Cancer News
NIH study illuminates origins of lung cancer in never smokers

6 September 2021, National Institute of Health

A genomic analysis of lung cancer in people with no history of smoking has found that a majority of these tumors arise from the accumulation of mutations caused by natural processes in the body. These insights will help unlock the mystery of how lung cancer arises in people who have no history of smoking and may guide the development of more precise clinical treatments...

New research shows a link between cell identities and childhood cancer type neuroblastoma

7 September 2021, ScienceDaily

Neuroblastoma is a type of childhood cancer that develops in infants and young children. Whilst it is a relatively rare form of cancer, it is still responsible for approximately 15 percent of all cancer deaths in children. Researchers have discovered that low-risk and high-risk neuroblastoma have different cell identities, which can affect the survival rate...

Novel tool counts T cells quickly helping predict patient response to cancer therapy

08 September 2021, EurekAlert

Scientists at UCL and the Francis Crick Institute, London, have developed a new tool, which can rapidly estimate the number of T cells (immune cells) in a cancerous tumour with T cell abundance helping predict a patient’s response to immunotherapy, researchers are hopeful this could enable more targeted and effective cancer therapies...

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