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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image14 June 2021 Vol. No. 10; Issue No. 479

1. Gupta S, Rajappa S, Advani S, Agarwal A, Aggarwal S, Goswami C, Palanki SD, Arya D, Patil S, Kodagali R (2021). Prevalence of BRCA1 and BRCA2 mutations among patients with ovarian, primary peritoneal, and fallopian tube cancer in India: A multicenter cross-sectional study. JCO Global Oncology.7: 849-861.

2. Shylasree TS, Ranade R, Kattepur AK, Kaur S, Dusane R, Maheshwari A, Mahantshetty U, Chopra S, Engineer R, Kerkar RA (2021). Quality of life in long term survivors of cervical cancer: A cross sectional study. Indian Journal of Cancer. 58: 171-8.

3. Joshi R, Thomas M, Patkar S, Gupta A, Panhale K, Rane P, Ambulkar R, Goel M, Shrikhande S, Agarwal V (2021). Impact of enhanced recovery pathway in 408 gallbladder cancer resections. HPB.

Site of the Week

VecScreen is a system that quickly finds segments of a nucleic acid sequence that may be of vector origin. It helps researchers identify and remove any segments of vector origin before they analyze or submit sequences.

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Interesting Reads

Kato T, Ono H, Fujii M, Akahoshi K, Ogura T, Ogawa K, Ban D, Kudo A, Tanaka S, Tanabe M. Cytoplasmic RRM1 activation as an acute response to gemcitabine treatment is involved in drug resistance of pancreatic cancer cells. PLoS One. 16(6):e0252917, 2021.

Legends of Science
Rudolf Ludwig Carl Virchow Bhudeb Chandra Basu

Bhudeb Chandra Basu obtained his DSc(1935) from University of kolkata. His specialization was Entomology. His research was on human and avian malaria, human filariasis, rat bite fever, fowl cholera, anthrax, surra. His significant contribution was in the areas of transmission, parasitology, treatment, prophylactics, disease and insect control. He was Entomologist, Bengal Public Health Department, School of Tropical Medicine, Kolkata, Research officer, Indian Veterinary Research Institute, President (1950), Indian Science Congress.

Andreas Vesalius Kameshwar Sahai Bhargava

Kamaleshwar Sahai Bhargava obtained his PhD(1948) from University of London, UK. He specialized in areas of mycology, pathology and virology. He studied the virus diseases of temperate fruits, cucurbits and sugarcane. He worked on the ecology and natural spread of the casual viruses and their relationship with insect vectors. He studied the antiviral activity of certain ferns. He was the President, Indian Phytopathological Society, Indian Virological Society. He was the recipient of Panchanan Maheshwari Medal (1981), Mundkur Lecture award, Indian Phytopathological Society.

Do You Know?

In 2011, A study introduced the concept of ‘senescence surveillance’, wherein premalignant senescent hepatocytes are cleared through a tumour-antigen-directed immune response.

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Cancer News
Cholesterol metabolite induces production of cancer-promoting vesicles

09 June 2021, MedicalXpress

Scientists working to understand the cellular processes linking high cholesterol to breast cancer recurrence and metastasis report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells…

Astronomy meets pathology to identify predictive biomarkers for cancer immunotherapy

10 June 2021, ScienceDaily

Pairing sky-mapping algorithms with advanced immunofluorescence imaging of cancer biopsies, researchers developed a robust platform to guide immunotherapy by predicting which cancers will respond to specific therapies targeting the immune system…

Promising ovarian cancer treatment proves effective and efficient

11 June 2021, EurekAlert

In the study, researchers utilized a new generator system to develop the targeted alpha-therapy Pb-214-TCMC-trastuzumab to treat HER2-postive ovarian cancer. Ovarian cancer cells and mice bearing ovarian cancer tumors were split into three groups…

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