Top Image
Advanced Centre for Treatment Research & Education in Cancer
Facebook Twitter Gmail
Banner Image
Science Sparks @ ACTREC
Date Image 15 February 2021 Vol. No. 10; Issue No. 462

1. Shabrish S, Mittra I (2021). Cytokine storm as a cellular response to dsDNA breaks: A new proposal. Frontiers in Immunology. 12: 622738.

2. Nair NS, Penumadu P, Yadav P, Sethi N, Kohli PS, Shankhdhar V, Jaiswal D, Parmar V, Hawaldar RW, Badwe RA. (2021). Awareness and acceptability of breast reconstruction among women with breast cancer: A prospective survey. JCO global oncology, 7, 253–260.

3. Swain M, Ghosh-Laskar S, Budrukkar A, Patil R, Murthy V, Gupta T, Mummudi N, Prabhash K, Joshi A, Patil VM, Naronha V, Agarwal JP (2021). Concurrent chemoradiotherapy for locally advanced unresectable adenoid cystic carcinoma of head and neck: experience from a single institute. European Archives of Oto-Rhino-Laryngology.

4. Patkar N, Kakirde C, Shaikh AF, Salve R, Bhanshe P, Chatterjee G, Rajpal S, Joshi S, Chaudhary S, Kodgule R, Ghoghale S, Deshpande N, Shetty D, Khizer SH, Jain H, Bagal B, Menon H, Khattry N, Sengar M, Tembhare P, Subramanian P, Gujral S (2021). Clinical impact of panel-based error-corrected next generation sequencing versus flow cytometry to detect measurable residual disease (MRD) in acute myeloid leukemia (AML). Leukemia.

5. Bishnu A, Phadte P, Dhadve A, Sakpal A, Rekhi B, Ray P (2021). Molecular imaging of the kinetics of hyperactivated ERK1/2-mediated autophagy during acquirement of chemoresistance. Cell Death & Disease. 12(2): 161.

6. Gupta T, Sinha, S, Chinnaswamy G, Vora T, Prasad M, Bhat V, Goda JS, Krishnatry R, Chatterjee A, Epari S, Sahay A, Moiyadi A, Shetty P, Patil V, Khatua S, Jalali R, Kurkure P. (2021). Safety and efficacy of concurrent carboplatin during full-dose craniospinal irradiation for high-risk/metastatic medulloblastoma in a resource-limited setting. Pediatric Blood & Cancer: e28925.

7. Bandekar B, Awatagiri K, Kannan S, Rane P, Parikh P. Audit of principal investigator's compliance for submission of continue review application and decisions taken on lapses in validity of approval by the Institutional Ethics Committee at tertiary oncology center in Navi Mumbai. Perspectives in Clinical Research.

8. Shetty D, Talker E, Jain H, Patil S, Tembhare P, Patkar N, Nayak L, Jain H, Sengar M (2021). Additional Cytogenetic Aberrations Indicative of Poor Prognosis in AML with RUNX1/RUNX1T1 Rearrangement: Karyotype a Chromosomal Blueprint. Annals of Hematology and Oncology. 8(1): 1325.

9. Ramanujam P, Mehrotra S, Kumar R, Verma S, Deshpande G, Mishra R, Galande S (2021). Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes. Scientific Reports. 11:3385.

Site of the Week

SugarSketcher is designed to provide users with a simple and efficient interface for drawing glycan molecules with the logos defined in the Symbol Nomenclature for Glycans (SNFG).

desktop Image
Interesting Reads

Adam K, Iuga A, Tocheva AS, Mor A. A novel mouse model for checkpoint inhibitor-induced adverse events. PLoS One. 16(2) :e0246168, 2021.

Legends of Science
Rudolf Ludwig Carl Virchow Jyotirmoy Das

Jyotirmoy Das obtained his DSc degree from University of Kolkata (1982). His specializations were Molecular biology and Biophysics. He demonstrated the DNA repair mechanism in Vibrio Cholerae and identified genes involved in these processes. He contributed significantly to the elucidation of V cholerae genome structure, identification of genomic rearrangements and diversity. He further went on to construct an ordered cloned DNA map of V cholerae genome. He is also credited with the development of an oral vaccine strain for cholera. He was Director, IICB, Kolkata (1995-1998). He was the recipient of the Ranbaxy Research Foundation Award (1989), Om Prakash Bhasin Award (1990).

Andreas Vesalius Ramamirtha Jayaraman

Ramamirtha Jayaraman obtained his PhD from Tufts University, Boston (1970). He was Bacterial Geneticist. His specialization was bacteria especially escheria coli. His main research was on transcription and its regulation in E.coli. He developed a genetic assay for gene-specific mRNAs of Bacteriophage T4. He was the first one to show the role of accessory transcription factors in E coli. He authored the reference manual, ‘Jayaraman Laboratory Manual in Molecular Genetics’. He was the recipient of Shanti Swarup Bhatnagar award (1982).

Do You Know?

In 1881, The discovery by Louis Pasteur that cultures of Pasteurella multocida bacteria gradually lost their virulence over time, which he named ‘attenuation’, led to the first experiments involving immunization with live attenuated Bacillus anthracis.

back Image
Cancer News
Halt cell recycling to treat cancer

08 February 2021, ScienceDaily

Targeting and changing autophagy, otherwise known as cell recycling, has been linked to helping control or diminish certain cancers. Now, researchers have shown that completely halting this process in a very aggressive form of breast cancer may improve outcomes for patients one day...

Researchers discover previously-unknown function in enzyme critical for cancer growth

11 February 2021,

Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations…

Promising new approach to stop growth of brain cancer cells

12 February 2021, EurekAlert

The inhibition of PRMT5 led to cell senescence, similar to what happens to cells during aging when cells lose the ability to divide and grow. Cellular senescence can also be a powerful tumour suppression mechanism, stopping the unrelenting division of cancer cells...

2021 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)