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Science Sparks @ ACTREC
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 17th January 2022 |
Vol. No. 11; Issue No. 509 |
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Publications
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1. Bal M, Shah A, Rekhi B, Mittal N, Rane SU, Rabade K, Shetty O, Pantavaidya G, Nair D, Prabhash K, Aishwarya M, Govindarajan KK, Laskar S, Laskar SG, Patil A. (2022) Adamantinoma-Like Ewing Sarcoma of the head and neck: A case-series of a rare and challenging diagnosis. Head and Neck Pathology.
2. Soh KT, Came N, Otteson GE, Jevremovic D, Shi M, Olteanu H, Natoni A, Lagoo A, Theakston E, Óskarsson JÞ, Gorniak M, Grigoriadis G, Arroz M, Fletcher M, Lin P, Ludwig P, Tembhare P, Matuzeviciene R, Radzevicius M, Kay S, Chen W, Cabrita C, Wallace PK. (2022) Evaluation of multiple myeloma measurable residual disease by high sensitivity flow cytometry: An international harmonized approach for data analysis. Cytometry Part B: Clinical Cytometry.
3. Vishwakarma GK, Kumari P, Bhattacharjee A. (2022) Thresholding of prominent biomarkers of breast cancer on overall survival using classification and regression tree. Cancer Biomarkers.
Book Chapters
1. Pansare K, CM Krishna. “Monitoring Therapeutic Response in Cancers: A Raman Spectroscopy Approach” In: Rahman A, Ozkan S (Eds.). Recent Advances in Analytical Techniques. Vol. 5, Bentham Science Publishers, 2022. Pp. 192-275. (ISBN: 978-9815036947)
2. Shabrish S, Madkaikar M. "Comprehensive evaluation of NK cells and its utility in the diagnosis of NK cell defects" In: Duncan LT (Ed.) Advances in Health and Disease. Volume 46, New York; Nova Science Publishers, 2021. Pp. 103-154. (ISBN 978-1-68507-266-7)
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Legends of Science
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Viswanathan Sasisekharan
Viswanathan Sasisekharan obtained his Ph.D. from the University of Madras in 1959. He has significant work on confirming biopolymers, especially polynucleotides and polypeptides. He developed incisive methods for arriving at the optimal conformation of macromolecules. Based on these methods, he has suggested a new alternative model for the Watson-Crick double-helical structure of DNA. Dr. Sasisekharan received the Shanti Swarup Bhatnagar award in 1978; the J C Bose award in 1985; Fogarty Scholar in Residence, NIH in 1988-90.
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Virendra Nath Pandey
V N Pandey, a molecular virologist, and geneticist secured his Ph.D. from Mumbai University in 1985. Dr. Pandey has demonstrated the presence of a DNA recombinase enzyme complex associated with the thymic nuclear matrix of young rats. The complex occurs explicitly in prelymphocytes and is presumably involved in the rearrangement and recombination of genes to generate immunodiversity in vertebrates. He was the recipient of the Shanti Swarup Bhatnagar Award in 1991.
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Do You Know?
In 1869, Friedrich Miescher first identified "nuclein" in the nuclei of human white blood cells, today which is called as deoxyribonucleic acid (DNA).
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Cancer News
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Identification of a novel therapeutic target in Multiple Myeloma
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12 January 2022, EureKAlert
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Using murine models and tumors from patient biopsies, researchers demonstrated that mycolactone is highly toxic to multiple myeloma cells, including those that have become resistant to proteasome inhibitors, at doses that are non-toxic to normal cells...
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Nuclei-free cells prove utility in delivering therapeutics to diseased tissues
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14 January 2022, MedicalXpress
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Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health report successfully removing the nucleus out of a type of ubiquitous cell, known as enucleation, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues...
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The first AI breast cancer sleuth that shows its work
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14 January 2022, Sciencedaily
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Researchers have developed an artificial intelligence platform to analyze potentially cancerous lesions in mammography scans to determine if a patient should receive an invasive biopsy...
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© 2022 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
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