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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 18th October 2021 Vol. No. 10; Issue No. 497

1. Dhadve A, Ray P (2022). An active RUNX1-ID1/ID3 axis governs differentiation and chemoresistance of cancer stem cell population in epithelial ovarian cancer cells. Biocell. 46(1): 75-86.

2. Rashid M, Shah SG, Natu A, Verma T, Rauniyar S, Gera PB, Gupta S (2021). RPS13, a potential universal reference gene for normalisation of gene expression in multiple human normal and cancer tissue samples. Molecular Biology Reports.

3. Patwardhan S, Mahadik P, Shetty O, Sen S (2021). ECM stiffness-tuned exosomes drive breast cancer motility through thrombospondin-1. Biomaterials.

Site of the Week

SUPERFAMILY is a database of structural and functional annotation for all proteins and genomes.

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Interesting Reads

Lenz HJ, Van Cutsem E, Luisa Limon M, Wong KYM, Hendlisz A, Aglietta M, García-Alfonso P, Neyns B, Luppi G, Cardin DB, Dragovich T, Shah U, Abdullaev S, Gricar J, Ledeine JM, Overman MJ, Lonardi S. First-Line Nivolumab Plus Low-Dose Ipilimumab for Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Phase II CheckMate 142 Study. J Clin Oncol. 2021 .

Legends of Science
Mahadeo Atmaram Moghe Mahadeo Atmaram Moghe

Mahadeo Atmaram Moghe obtained his Ph.D. from the University of London, UK, in 1937. His specialization was Embryology. His main contribution was the research on taxonomy of helminth parasites, specially cestodes from vertebrates. He carried out a survey of the incidence of helminth infection in cattle, goats, and sheep. His other research areas were cytochemistry, histology, development of the mammalian placenta, chromosomes, and spermatogenesis in homopterous and heteropterous insects. At National Environmental Engineering Research Institute, Dr. Moghe initiated and developed studies on biological aspects of problems with the sewage water. Dr. Moghe was the President of Zoology and Entomology Section of the Indian Science Congress in 1947.

Suhrit Chandra Mitra Suhrit Chandra Mitra

Suhrit Chandra Mitra secured his DPhil from the University of Leipzig, Germany, in 1924. He was specialized in experimental Psychology. He made extensive studies on the topics such as the theory of emotion, psychology and unemployment, the concept of instinct and experiments on Fechner's paradox. Dr. Mitra was a member, Deutsche Philispphisce Gesselschaft: Secretary, Indian Psychological Association and International Psychoanalytical Society. He was the President of Psychology Section, Indian Philosophical Congress in 1934 and Indian Science Congress in 1935.

Do You Know?

In 1992, a surgical technique called sentinel lymph node became a less invasive way to assess whether cancer has spread in patients with early-stage melanoma, the most aggressive form of skin cancer.

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Cancer News
BRCA1 mRNA expression in breast and colorectal cancer

12 October 2021, EurekAlert

LMNB2 is a chromatin remodeling protein that also plays a role in eukaryotic cell proliferation by organizing the nuclear membrane during mitosis...

Clinical trial demonstrates focused ultrasound can deliver antibody therapy to breast cancer metastases in the brain

13 October 2021, MedicalXpress

In a first in -world clinical trial, researchers at Sunnybrook Health Sciences Centre in Toronto, Canada, have demonstrated that magnetic resonance (MR)-guided focused ultrasound can be used to safely deliver antibody therapy to breast cancer that has metastasized to the brain...

Solving mystery of rare cancers directly caused by HIV

13 October 2021, Sciencedaily

When HIV enters the body, it seeks out T cells and inserts its genetic sequence called the "provirus" into the cell's DNA. This effectively hijacks the T cells, which normally patrol the body in search of foreign pathogens, instead instructing them to produce more HIV...

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