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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 19 July 2021 Vol. No. 10; Issue No. 484

1. Mishra SK, Hole A, Reddy BPK, Srivastava R, CM Krishna, De A.( 2021) Raman Micro-spectroscopic Map estimating in vivo precision of tumor ablative effect achieved by photothermal therapy procedure. Nanomedicine: Nanotechnology, Biology and Medicine.

2. Paul R, Bapat P, Deogharkar A, Kazi S, Singh SKV, Gupta T, Jalali R, Sridhar E, Moiyadi A, Shetty P, Shirsat NV (2021). MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of group 4 medulloblastoma. Human Molecular Genetics.


Rohit Srivastava, Deepak Singh Chauhan, Radhika Poojari, Aravind Kumar Rengan, Abhijit De, Amirali Bakarali Bukhari, Asifkhan Shanavas, "TPGS Comprised gold coated Poly - (LACTIC-CO-GLYCOLIC ACID) nanostructures and process for its preparation", Indian Patent 354678, Dec. 29, 2020.

Site of the Week

exoRBase is a repository of circular RNA (circRNA), long non-coding RNA (lncRNA) and messenger RNA (mRNA) derived from RNA-seq data analyses of human blood exosomes.

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Interesting Reads

Hou K, Shen J, Yan J, Zhai C, Zhang J, Pan JA, Zhang Y, Jiang Y, Wang Y, Lin RZ, Cong H, Gao S, Zong WX. Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin. EBioMedicine. 69:103456, 2021.

Legends of Science
Rudolf Ludwig Carl Virchow Virender Lal Chopra

Virender Lal Chopra was a Graduate from Central College of Agriculture, Delhi, in 1955. He went to the Institute of Genetics, the University of Cologne, on scholarship and obtained his doctorate in Genetics from the University of Edinburgh. His specialization was in the Genetic effects of irradiated or chemically treated media in Drosophila and microorganisms. He was In-Charge of the planning and management of research in Genetics and Biotechnology in IARI. He was a member of the scientific advisory committee to the prime minister of India. Because of his outstanding contributions, he was conferred with Padma Bhushan in 1985 by the Government of India. He is the recipient of the Borlaug Award, Om Prakash Bhasin Award, and Honor Summus Medal of the Watumull Foundation, USA. He was the Fellow of The World Academy of Sciences in 1989 and was honored by four universities with honorary doctorates.

Andreas Vesalius Sachindananda Banerjee

Sachindananda Banerjee obtained his DSc from the University of Kolkata in 1945. He specialized in physiology and nutrition. He determined that the structure of camel hemoglobin differs from any other hemoglobin. He demonstrated that vitamin C deficiency in Guinea pigs and monkeys led to diminished insulin secretion and produced metabolic changes similar to those of diabetes in human beings. He also found the calorie requirements of Indians under different occupancies and demonstrated the unsuitability of FAO standards for Indians. He was the Head of the Physiology Department, SMS Medical College, Jaipur, and shouldered responsibility at SP Medical College, Bikaner and, Department of Physiology in Presidency College, Kolkata.

Do You Know?

In 2004, Azacitidine, an inhibitor of DNA methylation and a pioneering epigenetic therapy, became the first drug to gain US Food and Drug Administration (FDA) approval for the treatment of myelodysplastic syndrome.

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Cancer News
Quantum physics helps destroy cancer cells

14 July 2021, ScienceDaily

Cancer cell death is triggered within three days when X-rays are shone onto tumor tissue containing iodine-carrying nanoparticles. The iodine releases electrons that break the tumor's DNA, leading to cell death...

Drug combination shows meaningful responses for malignant peritoneal mesothelioma patients

14 July 2021, MedicalXpress

A phase II study led by researchers from The University of Texas MD Anderson Cancer Center found that treatment with atezolizumab and bevacizumab was well-tolerated and resulted in a 40% objective response rate in patients with advanced malignant peritoneal mesothelioma, a rare cancer in the lining of the abdomen…

For Kids with Medulloblastoma, trial Suggests radiation can be tailored

16 July 2021, National Cancer Institute

Results of a large clinical trial suggest that some kids can safely get less radiation without limiting their long-term survival, whereas others may need the standard doses…

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