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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 21 March 2022 Vol. No. 11; Issue No. 518

1. Gupta T, Kalra B, Goswami S, Deodhar J, Rane P, Epari S, Moidadi A, Dasgupta A, Chatterjee A, Chinnaswamy G (2022). Neuro-cognitive function and survival in children with average-risk medulloblastoma treated with hyperfractionated radiation therapy alone: long-term mature outcomes of a prospective study. Neuro-Oncology Practice.

2. Shah M, Noronha V, Ramaswamy A, Gattani S, Mokal S, Joshi A, Patil V, Menon N, Banavali S, Badwe R, Prabhash K (2022). G8 and VES-13 as screening tools for geriatric assessment and predictors of survival in older Indian patients with cancer. Journal of Geriatric Oncology.

3. Gupta T, Maheshwari G, Kannan S, Nair S, Agarwal JP (2022). Should sentinel lymph node biopsy be considered the new standard of care for early-stage clinically node-negative oral squamous cell carcinoma? Journal of Clinical Oncology.

1. Sanketkumar Girishkumar Shah. 2022. Deciphering the transcriptional regulation of differentially expressing H2A isoform. (HBNI No.:LIFE09201504021) (Guide: Dr. Sanjay Gupta)

2. Mudasir Rashid. 2022. Delineating the molecular mechanism(s) involved in regulating the expression of H3 genes in Human cancer. (HBNI No.: LIFE09201504014) (Guide: Dr. Sanjay Gupta)

Site of the Week

Genomes OnLine Database is a World Wide Web resource for comprehensive access to information regarding genome and metagenome sequencing projects, and their associated metadata, around the world.

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Interesting Reads

Labrie M, Brugge JS, Mills GB, Zervantonakis I (2022). Therapy resistance: opportunities created by adaptive responses to targeted therapies in cancer. Nat Rev Cancer.

Legends of Science
Usha Vijayraghavan Usha Vijayraghavan

Usha Vijayraghavan obtained her Ph.D. from the California Institute of Technology. Her research interest was in plant genetics; she worked on genes that regulate flowering and plant morphology. Her group uses molecular genetics and functional genomics to understand various aspects of how gene activity is regulated in yeasts and plants. Dr. Vijayraghavan has been awarded several awards like DBT-Bioscience Award; J.C. Bose Fellowship; Sir C. V. Raman Award, and Rockefeller Foundation Biotechnology Career Fellowship.

Kasturi Datta Kasturi Datta

Kasturi Datta earned her Ph.D. from Kolkata University. Her research interest was in understanding the molecular basis of cell-matrix proteins in cell-cell interaction and signal transduction under environmental stimuli. Her group purified and identified a novel protein having a specific affinity towards hyaluronan. She characterized this protein confirming its multifunctionality, its role in cellular signaling, and apoptosis induction. Dr. Dutta is an elected member of the American Society of Biological Chemistry and Molecular Biology. She is a Fellow of the Indian Academy of Science, Bangalore; Academy of Sciences for the developing world (TWAS). She is the recipient of the Ranbaxy Award (1991); Senior Women Bioscientist Award of DBT (2001) and FICCI Award (2004).

Upcoming Events
44th Indian Biophysical Society Meeting (IBS 2022)

30 March-1 April, 2022

At ACTREC, Tata Memorial Centre, Navi Mumbai

Gordon Research Conference — Nasopharyngeal Carcinoma

08-13 May, 2022

At Castelldefels, Spain

EMBO Workshop — The Many Faces of Cancer Evolution

20-22 May, 2022

At Rimini, Italy

Do You Know?

In 2007, researchers determined that at least 12 lymph nodes need to be removed and analyzed during colon cancer surgery to accurately determine the stage of tumor.

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Cancer News
Programming the immune system to supercharge cancer cell therapies

16 March 2022, ScienceDaily

Scientists have developed a genetic screening platform to identify genes that can enhance immune cells to make them more persistent and increase their ability to eradicate tumor cells...

Burst of rapid cell motion in 3D tumor model could explain cancer metastasis

16 March 2022, MedicalXpress

The researchers designed their model system using clumps of cervical cancer cells in simple 3D tissues that they could control, enabling them to systematically study the behavior of the cells in different pressures and environments...

Another step toward blood-based screening for colorectal cancer

16 March 2022, Clinical Oncology News

The test aims to identify cancer-related genomic alterations and epigenomic modifications (methylation and modifications in chromatin state); results are given as “ctDNA detected” or “ctDNA not detected.”...

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