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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 22 March 2021 Vol. No. 10; Issue No. 467

1. Sengupta A, Gupta S, Sharda A, Hemant S, Ingle A (2021). Effect of low frequency electrical current on the biophysical and molecular properties of cancer cells. International Journal of Cancer and Clinical Research. 8:145.

2. Rashid M, Shah SG, Verma T, Chaudhary N, Sukanya, Patel VB, Gera PB, Smoot D, Ashaktorab H, Dalal SN, Gupta S (2021). Tumor-specific overexpression of histone gene, H3C14 in gastric cancer is mediated through EGFR-FOXC1 axis.Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms.13:19470

3. Lewis S, Pandey S, Salins N, Deodhar J, Patil V, Gupta T, Laskar SG, Budrukkar A, Murthy V, Joshi A, Prabhash K, Nair S, Chaturvedi P, Noronha V, Agarwal JP (2021). Distress screening in head and neck cancer patients planned for cancer-directed radiotherapy. Laryngoscope.

4. Patel U, Mittal N, Rane S, Patil A, Gera P, Kannan S, Joshi A, Noronha V, Patil V, Prabhash K, Mahimkar M (2021).Correlation of transcriptionally active human papillomavirus status with the clinical and molecular profiles of head and neck squamous cell carcinomas. Head and Neck.

5. Swamidas J, Rose J, Chopra S, Paul SN, Joshi K, Panda S, Phurailtlatpam R, Agarwal JP. Implementation of a visual feedback system for motion management during radiation therapy. Journal of Cancer Research and Therapeutics. 17:148-51.

6. Harish M, Venkatraman P (2021). Evolution of biophysical tools for quantitative protein interactions and drug discovery. Emerging Topics in Life Sciences.

7. Shetty D, Mohanty P, Talker E, Jain H, Chaubal K, Tembhare P, Patkar N, Subramanian P, Moulik NR, Dhamne C, Narula G, Banavali S (2021). Importance of conventional cytogenetics in the identification of ins(19;X)(q13.1;p11.2q28) and t(1;11)(q10;p10), both, novel cytogenetic abnormalities in a pediatric AML case. Cancer Genetics.

Site of the Week

CancerResource is a comprehensive knowledgebase for drug-target relationships related to cancer as well as for supporting information or experimental data.

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Interesting Reads

Lafontaine DLJ, Riback JA, Bascetin R, Brangwynne CP (2021). The nucleolus as a multiphase liquid condensate. Nat Rev Mol Cell Biol. 22(3):165-182.

Legends of Science
Rudolf Ludwig Carl Virchow Krishna Kamini Rohatgi-Mukherjee

Krishna Kamini Rohatgi-Mukherjee obtained her DPhil from University of Oxford, UK. She was Professor at Jadavpur University, Kolkata. Her work on photoreaction between anthracene and CC14 led to concept of photo-induced electron transfer mechanism. She carried out studies on photo physical properties of molecules in electronically excited singlet and triplet states; singlet oxygen and photodynamic action, photo electrochemistry, photochemical conversion and storage of solar energy, photo physics and photochemistry of porphyrins, and photo-induced electron transfer in organized media, such as a polymers, micelles and liposomes. She was conferred with Sir CV Raman Award by Indian Science Congress Association (1991). She was President, Chemistry Section, Indian Science Congress and International Congress on Photobiology, Honorary Member (President, 1985-88), Association International de Photobiology. Rohatgi-Mukherjee’s early work on dye-aggregation and consequent hypochromism due to excitonic interaction won her international peer recognition.

Andreas Vesalius Aparna Gupta

Aparna Gupta obtained her PhD from Banaras Hindu University. She was Professor at the Department of Animal Biology, School of Life Sciences, University of Hyderabad. Her research areas were zoology, developmental Biology and endocrinology. She worked in the field of insect physiology, particularly pests and their control. Her main work was on an economically important group of insects. It included a large number of stored grain and agricultural pests. Her studies using biochemical and molecular tools unraveled the developmental and hormonal regulation of various genes, their proteins and the specific physiological processes in insects. Her group identified several candidate genes and their corresponding proteins, useful for delivering/ targeting molecules and growth regulators, which disrupt insect development and reproduction. She was a Fulbright Scholar, Indo-German Exchange Fellow, INSA-Czech Academy Exchange Fellow, INSA-DFG International Exchange Fellow, Hamburg University, Germany, NSA-JSPS Bilateral Exchange Fellow, Miyazaki University, Japan.

Do You Know?

A bivalent (influenza A and influenza B) whole inactivated vaccine was first approved for use in the military in 1945 and then for the general population in 1946.

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Cancer News
Electromagnetic fields hinder spread of breast cancer, study shows

17 March 2021, EurekAlert

The study is among the first to show that electromagnetic fields could slow or stop certain processes of a cancer cell's metabolism, impairing its ability to spread. The electromagnetic fields did not have a similar effect on normal breast cells...

Bacterial peptides presented on tumour cells could be immunotherapy targets

17 March 2021, Nature

Protein fragments from bacteria that invade tumour cells can be presented on the tumour-cell surface and recognized by the immune system. This discovery could have implications for cancer immunotherapies...

A leap forward in research on CAR T cell therapy

18 March 2021, MedicalXpress

In CAR T cell therapy, T cells are extracted from the patient for genetic modification: a chimeric antigen receptor (CAR) is transported into the cells using a viral vector, helping the T cells better identify and kill cancer cells...

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