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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 23rd May 2022 Vol. No. 11; Issue No. 527
Publications

1. Singh B, Roy Chowdhury S, Mansuri MS, Pillai SJ, Mehrotra S (2022). The BRCA2 and CDKN1A-interacting protein (BCCIP) stabilizes stalled replication forks and prevents degradation of nascent DNA. FEBS Letters.

2. Gupta SK, Jadhav S, Gohil D, Panigrahi G, Kaushal RK, Gandhi K, Patil A, Chavan P, Gota V (2022). Safety, toxicity and pharmacokinetic assessment of oral Withaferin-A in mice. Toxicology Reports.

3. Razis E, Escudero MJ, Palmieri C, Mueller V, Bartsch R, Rossi G, Gampenrieder SP, Kolberg HC, Zdenkowski N, Pavic M, Connolly RM, Rosset L, Arcuri J, Tesch H, Vallejos C, Retamales J, Musolino A, Del Mastro L, Christodoulou C, Aebi S, Paluch-Shimon S, Gupta S, Ohno S, Macpherson I, Ekholm M, Zaman K, Vidal M, Chakiba C, Fumagalli D, Thulin A, Witzel I, Kotecki N, Gil-Gil M, Linderholm B (2022). Assessment of the management of carcinomatous meningitis from breast cancer globally: a study by the Breast International Group Brain Metastasis Task Force. ESMO Open. 7(3): 100483.

Site of the Week

MADAP is a flexible clustering tool for the interpretation of one-dimensional genome annotation data mapped onto complete or partial genome sequences.

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Interesting Reads

Takáts A, Berke G, Gede N, Németh BC, Witt H, Głuszek S, Rygiel AM, Hegyi P, Sahin-Tóth M, Hegyi E. Risk of chronic pancreatitis in carriers of loss-of-function CTRC variants: A meta-analysis. PLoS One. 17(5):e0268859, 2022.

Legends of Science
Ghanashyam Swarup Ghanashyam Swarup

Ghanshyam Swarup Obtained his Ph.D. from the Tata Institute of Fundamental Research, Mumbai. He has done pioneering work on protein tyrosine phosphatases. His work on Src family tyrosine kinases showed their role in regulating actin cytoskeleton reorganization. Dr. Swarup was elected a fellow of the Indian Academy of Sciences, Bangalore, in 1995; he was elected a member of the Guha Research conference. He received the prestigious SS Bhatnagar award in 1996.

Valakunja Nagaraja Valakunja Nagaraja

Valakunja Nagaraja received his Ph.D. from the IISc, Bangalore, in 1981. His significant research interest includes DNA topoisomerases, topology modulation, and regulation of gene expression to understand the underlying molecular mechanisms and their importance in cellular function. Dr. Nagaraja is a fellow of the Indian National Science Academy; the Indian Academy of Sciences, and the National Academy of Sciences. He was the recipient of the SS Bhatnagar award recipient in 1999 and J C Bose medal in 2010.

Upcoming Events
The Mobile DNA Conference: Evolution, Diversity, and Impact

05-09 June, 2022

At Malahide, Ireland

Gordon Research Seminar — Endothelial Cell Phenotypes in Health and Disease

25-26 June, 2022

Castelldefels, Spain

Cell State Transitions: Approaches, Experimental Systems and Models

24-27 July, 2022

At Wiston House, West Sussex, UK

Do You Know?

In 2005, Two studies showed that the drug bortezomib(Velcade) shrinks tumous in nearly half of patients with mantle cell lymphoma, one of the rarest forms of non-Hodgkin lymphoma.

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Cancer News
Identifying DNA repair genes holds promise for improving cancer treatment

19 May 2022, MedicalXpress

These new findings shed new light on how cancer cells react to chemotherapy and radiotherapy, and also uncover a new way in which cancer can become resistant to targeted treatments...

Study identifies new molecular target for cancer therapy

20 May 2022, EurekAlert

Researchers have identified a new molecular drug target that could result in new cancer drugs with fewer side effects...

Cancer Origin Identified by Scientists Through Cell Surgery.

22 May 2022, SciTechDaily

Researchers proved , for the first time, that chromosomes getting caught in these membranes is a direct risk factor for the formation of cancerous cells. Understanding this risk can lead to more effective cancer prevention...

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