Top Image
Advanced Centre for Treatment Research & Education in Cancer
Facebook Twitter Gmail
Banner Image
Science Sparks @ ACTREC
Date Image 27 September 2021 Vol. No. 10; Issue No. 494

1. Menon N, Patil V, Noronha V, Joshi A, Bhattacharjee A, Satam B, Mathrudev V, Ghosh Laskar S, Prabhash K (2021). Quality of life in patients with locally advanced head and neck cancer treated with concurrent chemoradiation with cisplatin and nimotuzumab versus cisplatin alone – Additional data from a phase 3 trial. Oral Oncology. 122: 105517.

2. Mojindra R, Hole A, Iwasaki K, Noothalapati H, Yamamoto T, Krishna CM, Govekar R (2021). DNA fingerprint analysis of Raman Spectra captures global genomic alterations in Imatinib-resistant chronic myeloid leukemia: A potential single assay for screening Imatinib resistance. Cells. 10(10): 2506.

3. Mhatre S, Lacey B, Sherliker P, Chatterjee N, Rajaraman P, Goel M, Patkar S, Ostwal V, Patil P, Shrikhande SV, Chitkara G, Badwe R, Lewington S, Dikshit R (2021). Reproductive factors and gall-bladder cancer, and the effect of common genetic variants on these associations: a case-control study in India. International Journal of Epidemiology.

Site of the Week

SMPDB (The Small Molecule Pathway Database) is an interactive, visual database containing more than 30 000 small molecule pathways found in humans only.

desktop Image
Interesting Reads

Martin TD, Patel RS, Cook DR, Choi MY, Patil A, Liang AC, Li MZ, Haigis KM, Elledge SJ. The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation. Science. 373(6561):1327-1335, 2021.

Legends of Science
Praphulla Chandra Guha Praphulla Chandra Guha

Praphulla Chandra Guha obtained his DSc from the University of Kolkata in 1923. He did pioneering work on the synthesis of mono and sesqui-terpenoids and bridged bicyclic compounds. He also established preparative synthesis for antimalarials, sulpha drugs, local anesthetics, essential oils, and natural products. Dr. Guha was Chairman, Department of Organic Chemistry, Indian Institute of Science, Bangalore. He was the President of Chemistry section of the Indian Science Congress (1936).

Nuggehalli Raghuveer Moudgal Nuggehalli Raghuveer Moudgal

Nuggehalli Raghuveer Moudgal obtained his Ph.D. from the University of Madras in 1958. He specialized in the biochemistry of thyroid hormones. His pioneering work was the extensive use of characterized hormonal antibodies to unravel the specific function of LH and FSH in regulating the reproductive physiology of the intact animal and the mode of action of the hormone at the cellular and molecular level. Dr. Moudgal was Dean, Faculty of Science, IISc, Bangalore. He was the recipient of the BC Guha Award in 1975, Shanti Swaroop Bhatnagar Award in 1976.

Do You Know?

In 1999, FDA approved the groundbreaking drug trastuzumb (Herceptin) after research showed that adding the monoclonal antibody to chemotherapy dramatically increases survical for women with breast cancer that over-produces a protein called HER2.

back Image
Cancer News
Deep learning enhances cancer diagnostic tools

22 September 2021, EurekAlert

Researchers at the Beckman Institute Biophotonics Imaging Laboratory applied deep learning to polarization-sensitive optical coherence tomography to better detect cancer. OCT is a non-invasive imaging test that uses light waves to determine the properties of a biological sample...

Scientists develop artificial intelligence method to predict anti-cancer immunity

23 September 2021, ScienceDaily

Researchers and data scientists have developed an artificial intelligence technique that can identify which cell surface peptides produced by cancer cells called neoantigens are recognized by the immune system...

Therapy using dual immune system cells effectively controls neuroblastoma

23 September 2021, MedicalXpress

The researchers utilized CAR-T cell (chimeric antigen receptor-T cell) immunotherapy, which involves harvesting immune-system T cells from a patient and genetically re-engineering them in the lab to recognize targets on the surface of cancer cells when they are reinfused into patients...

© 2021 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)