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Science Sparks @ ACTREC
Date Image 28 March 2022 Vol. No. 11; Issue No. 519

1. Pandya R, Uppangala S, Salian S, Gupta S, Kalthur G, Schlatt S, Adiga SK (2022). Short-term hypothermic holding of mouse immature testicular tissue does not alter the expression of DNA methyltransferases and global DNA methylation level, post-organotypic culture. Frontiers in Endocrinology.

2. Bajpai J, Kashyap L, Vallathol DH, Das A, Singh M, Pathak R, Rath S, Sekar A, Mohanta S, Reddy A, Joshi S, Nandhana R, Ravind R, Wadasadawala T, Nair N, Ghosh J, Parmar V, Gulia S, Desai S, Shet T, Thakur M, Patil A, Sarin R, Gupta S, Badwe R (2022). Outcomes of non-metastatic triple negative breast cancers: Real-world data from a large Indian cohort. The Breast. 63:77-84.

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LIPID MAPS provides standardised methodologies for mass spectrometry analysis of lipids.

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Interesting Reads

Tsvetkov P, Coy S, Petrova B, Dreishpoon M, Verma A, Abdusamad M, Rossen J, Joesch-Cohen L, Humeidi R, Spangler RD, Eaton JK, Frenkel E, Kocak M, Corsello SM, Lutsenko S, Kanarek N, Santagata S, Golub TR. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science. 375(6586):1254-1261, 2022.

Legends of Science
Handahal Subbarao Savithri Handahal Subbarao Savithri

Handahal Subbarao Savithri received her Ph.D. from the Indian Institute of Science, Bangalore. She determined the genomic sequences of several viruses and their strategies of expression to understand their mechanisms of infection. Dr. Savithri was conferred with P S Sharma Memorial Award of the Society of Biological Chemists in 1991 and J. C. Bose Award in 2008. She was elected fellow of the Indian Academy of Sciences, Bangalore in 1992 and The National Academy of Sciences, Allahabad in 2000.

Veenita Bal Veenita Bal

Vinneta Bal obtained her MD from the Haffkine Institute, Mumbai. Her research interest includes infectious disease epidemiology, diagnostics, innate immunity to cell fate decisions in T cell, and macrophage biology. Dr. Bal is a well known scientist at the National Institute of Immunology, New Delhi. She was a member of the Prime Minister's task force for Women in Science under the Ministry of Science and Technology.

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Do You Know?

In 2007, researchers determined that at least 12 lymph nodes need to be removed and analyzed during colon cancer surgery to accurately determine the stage of tumor.

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Cancer News
In animal study, implant churns out CAR-T cells to combat cancer

24 March 2022, ScienceDaily

Researchers have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors. In a proof-of-concept study involving lymphoma in mice, the researchers found that treatment with the implants was faster and more effective than conventional CAR-T cell cancer treatment...

Spinal fluid sampling used to track treatment response in pediatric glioma

24 March 2022, EurekAlert

Researchers examined DNA floating in the plasma and CSF at various points in treatment and used a very sensitive machine called digital droplet polymerase chain reaction (ddPCR) to assess the fraction, called a variant allele fraction (VAF), of mutated DNA versus non-mutated...

Assessing the invasive and metastatic potential of cancer cells from a tissue section

25 March 2022, MedicalXpress

For the first time, a research group evaluated the motility and invasive capacity of cancer cells in cancer tissue sections removed from colorectal cancer patients...

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