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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 4th April 2022 Vol. No. 11; Issue No. 520

1. Menon NS, Noronha V, Patil VM, Joshi A, Bhattacharjee A, Kalra D, Laskar SG, Mathrudev V, Nawale K, Bhelekar AS, Prabhash K (2022). Quality of life in patients with locally advanced head and neck squamous cell carcinoma undergoing concurrent chemoradiation with once-a-week versus once-every-3-weeks cisplatin. Cancer Medicine.

2. Bahl A, Rajappa S, Rawal S, Bakshi G, Murthy V, Patil K (2022). A review of clinical evidence to assess differences in efficacy and safety of luteinizing hormone–releasing hormone (LHRH) agonist (goserelin) and LHRH antagonist (degarelix). Indian Journal of Cancer. 59 (Suppl S1):160-74.

3. Naseem A, Ahire S, Ingle A (2022). Multiplexing: An efficient way of genetic monitoring of laboratory mice using microsatellite markers. Agricultural Science Digest.

4. Shrivastav G, Datta D, Wadasadawala T, Rane P, Panda S, Pathak R, Scaria L, Krishnamurthy R, Sarin R. (2022). Clinical audit of breast cancer patients treated with helical tomotherapy for irradiation of the internal mammary chain. Journal of Radiotherapy in Practice.

Site of the Week

TIMER (Tumor IMmune Estimation Resource) is a comprehensive resource for systematical analysis of immune infiltrates across diverse cancer types.

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Interesting Reads

Odaka H, Hiemori K, Shimoda A, Akiyoshi K, Tateno H. CD63-positive extracellular vesicles are potential diagnostic biomarkers of pancreatic ductal adenocarcinoma. BMC Gastroenterol. 22(1):153, 2022.

Legends of Science
Avadhesha Surolia Avadhesha Surolia

Avadhesha Surolia earned his Ph.D. degree from Madras University in 1976. He discovered novel blood group and tumor antigen-specific lectins and made an original contribution to clarifying the energetics and mechanism of protein-sugar recognition. He popularized Protein A as a tool in immunology. He discovered the broad substrate specificity of a key enzyme of biotin biosynthesis from M. Tuberculosis. He was conferred an Honorary D Sc degree by Queen's University, Belfast, UK. He is the only Indian member of the International Glycoconjugate Organization. Dr. Surolia is the recipient of the S.S. Bhatnagar award in 1987; Om Prakash Bhasin Award for Biotechnology in 1993; B.K. Bachhawat Memorial Award 2007.

Samit Adhya Samit Adhya

Samit Adhya obtained his Ph.D. from the Albert Einstein College of Medicine, New York, in 1981. His research interest includes research on the transport of RNA molecules across mitochondrial membranes. His group showed that RIC is taken up and targeted to mitochondria of human cells in a biologically active form, inducing the import of intracellular tRNAs and correcting the respiratory defect caused by a pathogenic mitochondrial tRNA mutation. He participated in the CSIR-CNRS Collaborative Project on Genome Mapping of old world Leishmania (2000). He was elected a Fellow of the Indian Academy of Sciences, Bangalore.

Upcoming Events
The Cell Signaling in Cancer Conference: From Mechanisms to Therapy

15-19 May, 2022

At New Orleans, LA

American Society of Gene & Cell Therapy (ASGCT) 25th Annual Meeting

16-19 May, 2022

At Washington, D.C.

3rd International Conference on Cancer 2022

30 May-01 June, 2022

At Istanbul, Turkey

Do You Know?

In 2005, Researchers discovered that patients with tumors carrying a specific alteration in a gene known as MGMT benefit from temozolomide (Temodar) therapy.

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Cancer News
Triggering cellular apoptosis by optical targeting

30 March 2022, EurekAlert

In recent years, photoimmunotherapy has drawn much attention, which is a revolutionary treatment that skillfully utilizes light as well as the host’s immune system...

Study shows critical protein may play a role in origin of mesothelioma

30 March 2022, Medicalxpress

Mesothelioma is an aggressive cancer that occurs in a thin layer of tissue called the mesothelium, which covers most internal organs. Its primary cause is exposure to asbestos...

Researchers identify new targets for immunotherapy in colon cancer

31 March 2022, ScienceDaily

Scientists identify a pathway of immune cell inhibition that may provide the basis for novel approaches to immunotherapy of colon cancer. Their results also highlight important roles of the intestinal microbiota in the development of the disease...

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