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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 5 April 2021 Vol. No. 10; Issue No. 469

1. Jose J, Vishwakarma G, Bhattacharjee A (2021). Illustration of missing data handling technique generated from Hepatitis C induced hepatocellular carcinoma cohort study. Journal of King Saud University - Science.

2. Subedi R, Dhimal M, Budukh A, Chapagain S, Gyawali P, Gyawali B, Dahal U, Dikshit R, Jha AK (2021) Epidemiologic Pattern of Cancer in Kathmandu Valley, Nepal: Findings of Population-Based Cancer Registry, 2018. JCO Global Oncology. 443-452.

3. Noronha V, Ramswamy A, Gattani SC, Krishnamurthy MN, Menon N, Patil V, Gota V, Banavali S, Prabhash K (2021). Polypharmacy and potentially inappropriate medication use in older Indian patients with cancer: A prospective observational study. Cancer Research Statistics and Treatment. 4(1): 67-73.

4. Sharma P, Mahajan A, Rane S, Bhattarcharjee A (2021). Assessment of COVID-19 severity using computed tomography imaging: A systematic review and meta-analysis. Cancer Research Statistics and Treatment . 4: 78-87.

5. Bose A, Modi K, Dey S, Dalvi S, Nadkarni P, Sudarshan M, Kundu TK, Venkatraman P, Dalal SN (2021). 14-3-3γ prevents centrosome duplication by inhibiting NPM1 function. Genes to Cells

1. Ajit Chandrakant Dhadve (2021) Investigating the role of IGF-IR signalling in development and maintenance of chemoresistance in ovarian carcinoma. (HBNI No. LIFE 09201404011) (Guide: Dr. Pritha Ray).

2. Harish Shrikrishna Bharambe (2021) Molecular mechanism undelying the effect of miRNA expression on medulloblastoma cell behavior. (HBNI No. LIFE09201404008) (Guide: Dr. Neelam Shirsat).

Site of the Week

Neuroscience Information Framework provides the largest searchable collection of neuroscience data, the largest catalog of biomedical resources, and the largest ontology for neuroscience on the web.

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Interesting Reads

Johnston WT, Erdmann F, Newton R, Steliarova-Foucher E, Schüz J, Roman E. Childhood cancer: Estimating regional and global incidence. Cancer Epidemiol. 2021 71(Pt B):101662.

Legends of Science
Rudolf Ludwig Carl Virchow Baldev Singh

Baldev Singh obtained his MBBS (1927) from Punjab University, Lahore. He obtained MRCP (1930) from Royal College of Physicians, London, UK. Singh’s research interests were neural manifestations of high altitude, brain edema biofeedback, heat hyperpyrexia, yoga, sleep, consciousness, epilepsy, tissue culture, and neural regulation of visceral, autonomic and behavior. He developed an experimental model of human anemia. He carried out lesions in the cat thalamus by implanting radon seeds and recorded cortical EEG by implanted electrodes. He showed cortico-thalamic involvement in the genesis of spike and dome EEG responses as seen in human EEG’s by this animal mode. Dr Singh served on ICMR Scientific Advisory Board and International Brain Research Organization. Dr Singh was conferred with the Basanti Devi Amirchand Award by ICMR (1961), Padma Bhushan (1971). He was Honorary Member, American Neurological Association and also Honorary Consultant to the President and the Prime Minister of India.

Andreas Vesalius Vinodkant Shah

Vinodkant Shah obtained his MSc (1954) from MS University of Baroda and received the Chancellor’s Gold Medal for standing first in MSc. He obtained MS (Zoology) (1957) from the University of Minnesota, USA and PhD (1961) from Columbia University, New York. He worked at Brookhaven Laboratory, Long Island and Tufts University, Boston (1961-64). His research interest was in the fields of cell biology, cytogenetics, and genetics. He studied heterochromatin and its replication using autoradiography, DNA synthesis in isolated chloroplasts of Euglena. He also worked on cell cycle using anti-metabolites. He was appointed as Member, Board of Governors, United States Educational Foundation in India. Shah played an active role in improving science education particularly in biology in the state of Gujarat. He served as Secretary and later President of All India Cell Biology Association. Shah was twice awarded the KG Nayak Award and Vikram Sarabhai Award (1992). He was elected Vice President of the International Organization of Cell Biology as well as Asia-pacific Organization of Cell Biology.

Do You Know?

In 1991, A crucial technological advance enabled the creation of human papillomavirus (HPV) virus like particles in the lab, which were eventually used to generate the HPV vaccines that can prevent development of HPV related cancers.

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Cancer News
Protein rewires metabolism to block cancer cell death, may allow cancer spread

29 March 2021, ScienceDaily

One specific protein may be a master regulator for changing how cancer cells consume nutrients from their environments, preventing cell death and increasing the likelihood the cancer could spread, a study has shown...

Researchers develop new method for identifying mutational signatures in cancer

30 March 2021, EurekAlert

The new technique uses an application of artificial intelligence called machine learning, via a computer algorithm that accesses and analyzes data to uncover what they call SuperSigs, which are mutational signatures that reveal the genetic effects of the underlying contributors to cancer...

Indian surgeon’s groundbreaking cancer research saves the lives of 1000s of women

31 March 2021, The Better India

Dr. Indraneel Mittra, a surgeon with the Tata Memorial Hospital, led a groundbreaking 20-year research into the early detection of breast and cervical cancer in the 1990s...

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