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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 5 July 2021 Vol. No. 10; Issue No. 482

1. Sarkar S, Deodhar K, Budukh A, Bal M, Ramadwar M (2021). Assessing the histopathology reports of colorectal carcinoma surgery: An audit of three years with emphasis on lymph node yield. Indian Journal of Cancer.

2. Chatterjee M, Nakhate S, Trivedi B, Talole S (2021). Efficacy of Pulmonary telerehabilitation of cancer patients infected with Covid -19 virus: Preliminary data of a pilot study. Journal of Cancer Rehabilitation. 4: 50-53.

3. Ostwal V, Ramaswamy A, Bhargava P, Hatkhambkar T, Swami R, Rastogi S, Mandavkar S, Ghosh J, Bajpai J, Gulia S, Srinivas S, Rath S, Gupta S (2021). Cancer Aging Research Group (CARG) score in older adults undergoing curative intent chemotherapy: a prospective cohort study. BMJ Open. 2021 11(6):e047376.

4. Masurkar SA, Deogharkar A, Bharambe HS, Shirsat NV (2021). Downregulation of CRX, a Group 3-specific oncogenic transcription factor, inhibits TGF-β/activin signaling in medulloblastoma cells. Biochemical Biophysical Research Communications. 568:76-82.

5. Gupta T, Kannan S, Kalra B, Thakkar P (2021). Systematic review and meta-analysis of randomised controlled trials testing the safety and efficacy of convalescent plasma in the treatment of coronavirus disease 2019 (COVID-19): Evidence-base for practise and implications for research. Transfusion Medicine.

6. Budukh A, Maheshwari A, Bagal S, Singh A, Deodhar K, Panse N, Palyekar V, Dikshit R, Badwe R (2021). Factors influencing women to participate in cervical cancer screening by providing menstrual pads: A population-based study from rural areas of Maharashtra state, India. Indian Journal of Cancer.

7. Ranganathan P, Chinnaswamy G, Sengar M, Gadgil D, Thiagarajan S, Bhargava B, Booth CM, Buyse M, Chopra S, Frampton C, Gopal S, Grant N, Krailo M, Langley R, Mathur P, Paoletti X, Parmar M, Purushotham A, Pyle D, Rajaraman P, Stockler MR, Sullivan R, Swaminathan S, Tannock I, Trimble E, Badwe RA, Pramesh CS; National Cancer Grid of India (2021). The International Collaboration for Research methods Development in Oncology (CReDO) workshops: shaping the future of global oncology research. Lancet Oncology.

Abhilash N Deo (2021). Role of IGF1R in Ovarian Cancer Metastasis. (HBNI: LIFE09201504017) (Guide: Dr Pritha Ray)

Site of the Week

DisGeNET is a discovery platform containing one of the largest publicly available collections of genes and variants associated to human diseases.

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Interesting Reads

Qiu Y, Yang Y, Yang R, Liu C, Hsu JM, Jiang Z, Sun L, Wei Y, Li CW, Yu D, Zhang J, Hung MC. Activated T cell-derived exosomal PD-1 attenuates PD-L1-induced immune dysfunction in triple-negative breast cancer. Oncogene. 2021.

Legends of Science
Rudolf Ludwig Carl Virchow Sahay Ram Bose

Sahay Ram Bose obtained his PhD from the University of Kolkata. He specialized in Mycology. His research was on Polyporaceae, described 143 species of these. He studied ant fungi from termite nest found in islands of Chilika Lake. While studying nitrogen fixation in some species of trees, he discovered that Phoma casuarinae does not fix nitrogen directly from air. Dr. Bose attempted to isolate an antibiotic Polyporin simillar to Penicillin from Polypores Sanguineous. He was Director of CNRS, France from 1957-59. Later he was Professor at School of Tropical Medicine, Kolkata. Dr. Bose was a Fellow of Royal Society of Edinburgh. He was Vice-President, Mycology Section of International Botanical Congress, Stockholm.

Andreas Vesalius Bharat Bhushan Chattoo

Bharat Bhushan Chattoo obtained his PhD in Microbial Genetics from University of Delhi in 1976. His specialization was in the fields of Biotechnology, Genomics and Proteomics. He successfully expressed therapeutic proteins of pharmaceutical interest such as Hepatitis B Surface antigen and human epidermal Growth Factor in non-conventional yeasts. He was responsible for establishment of Sri Mata Vaishno Devi University, Jammu, residential and highly technical University. He established a Cluster Innovation Centre to encourage the interface of industry and entrepreneurship in Gujarat. He was awarded the Rockfeller Foundation Biotechnology Career Fellowship, STA fellowship from Japan Science and Technology Corporation. He was a member of Genetics Society of America, Review Panel of Indo-Swedish Collaboration in Biotechnology.

Do You Know?

In 2005, two landmark studies demonstrated that human cancer cells with mutations in the tumour-suppressor genes BRCA1 and BRCA2 are sensitive to poly (ADP–ribose) polymerase inhibitors.

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Cancer News
For advanced prostate cancer, radiopharmaceutical improves survival

29 June 2021, National Cancer Institute

In the study, participants who received the drug, called 177Lu-PSMA-617, along with other standard treatments lived longer than those who received only standard therapies: a median of 15.3 months versus 11.3 months...

Machine learning helps in predicting when immunotherapy will be effective

30 June 2021, ScienceDaily

Researchers have now developed machine learning models that can predict if someone is likely to respond positively to immunotherapy. In clinical settings, this could pave the way for personalized immunotherapy approaches for patients, as well as guidance on how to best combine immunotherapy with other treatments...

Development of the world's first digital model of a cancer cell

01 July 2021, MedicalXpress

The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer cell using the example of human lung adenocarcinoma and opens up completely new avenues in cancer research...

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