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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 6th December 2021 Vol. No. 10; Issue No. 504

1. Gupta T, Maheshwari G, Kannan S, Nair S, Chaturvedi P, Agarwal J. (2022) Systematic review and meta-analysis of randomized controlled trials comparing elective neck dissection versus sentinel lymph node biopsy in early-stage clinically node-negative oral and/or oropharyngeal squamous cell carcinoma: Evidence-base for practice and implications for research. Oral Oncology. 124: 105642.

2. Joshi A, Patil V, Noronha V, Bhattacharjee A, Menon N, Kumar A, Jain P, Mukadam S, Shrinivas A, Punia A, Abhyankar A, Agarwal A, Khaddar S, Rajpurohit A, Kanteti A, Ravind R, Das K, Talreja V, Dhumal S, Prabhash K (2021) Diclofenac versus tramadol for mucositis related pain in head and neck cancer patients undergoing concurrent chemoradiation – a phase 3 study. ecancer 15: 1318.

3. Mishra GA, Pimple SA, Mittra I, Badwe RA (2021). Screening for breast cancer: Cost-effective solutions for low- & middle-income countries. Indian Journal of Medical Research.

4. Gupta SK, Gohil D, Panigrahi GC, Vaykar S, Rane P, Chavan P, Gota V. (2021) Comparison of different autoanalyzers for the determination of lymphocyte and neutrophil counts in mouse blood. Drug Metabolism and Personalized Therapy.

5. Wadasadawala T, Mangaj A, Mokal S, Pathak R, Sarin R, Gaikar M, Nair N, Bajpai J, Joshi S, Gulia S (2021). Measuring satisfaction in breast cancer patients receiving ambulatory care: A validation study. Indian Journal of Medical and Paediatric Oncology.


Shalini K.S. 2021. Understanding the Crosstalk of Mesenchymal Stem Cells and Gamma Delta T Cells in the Tumor Microenvironment. (HBNI No.: LIFE09201404004). (Guide Dr Shubhada Chiplunkar)

Site of the Week

Phenol-Explorer is the first comprehensive database on polyphenol content in food. The database contains more than 35,000 content values for 500 different polyphenols in over 400 foods.

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Interesting Reads

Sarrió D, Martínez-Val J, Molina-Crespo Á, Sánchez L, Moreno-Bueno G. The multifaceted roles of gasdermins in cancer biology and oncologic therapies. Biochim Biophys Acta Rev Cancer. 11876(2):188635, 2021.

Legends of Science
Vanmali Saran Manglik Vanmali Saran Manglik

Vanmali Saran Manglik obtained his MD from the University of Lucknow in 1929. His research was especially on tumor biology, bacteriology of epidemic gastroenteritis, and liver disorders. He was the pioneer in the internship program at the University of Lucknow Hospital, under the sponsorship of The Rockefeller Foundation. He served as the District Medical Officer, Agra Medical School. He was instrumental in setting up the Pathology department under the auspices of WHO in the Medical college in Myanmar.

Lakshminarayanapuram Krishna Iyer Ramachandran Lakshminarayanapuram Krishna Iyer Ramachandran

LKI Ramachandran obtained his Ph.D. from the University of Madras in 1953. His research topics were the structure of tobacco virus protein, protein iodine interactions, and amino acids and toxins in the Lathyrus species of plants. He made significant contributions to structure-activity correlations in peptide antibodies and toxins of venoms. He was a Member of the Society of Biological Chemists; American Chemical Society; New York Academy of Sciences. Dr. Ramachandran was conferred with the P. S. Sarma Memorial Award by the Society of Biological Chemists in 1973; Sir J C Bose Award in 1978.

Do You Know?

In 2010, Initial results of the NCI-sponsored Lung Cancer Screening Trial (NLST) showed that screening with low-dose helical computerized tomography (CT) reduced lung cancer deaths by about 20% in a large group of current and former heavy smokers.

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Cancer News
Changing the identity of cancer cells to eliminate them

01 December 2021, EurekAlert

A team led by the University of Pennsylvania’s M. Andrés Blanco has uncovered a new target for treating certain blood cancers that works by removing an obstacle to their maturation…

Harnessing the organization of the cell surface

02 December 2021, ScienceDaily

Scientists have developed a new method to determine how proteins are organized on the surface of cells. Insights gained with the technology could lead to the development of novel drugs to fight cancer...

Molecular aspects of ovarian and endometrial tumors mapped to the level of a single cell

03 December 2021, MedicalXpress

Researchers used single-cell sequencing to measure the genetic and epigenetic states of more than 150,000 individual cells from 11 ovarian and endometrial tumor samples that were sequenced on the same day they were surgically removed from the patients...

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