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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 8 February 2021 Vol. No. 10; Issue No. 461

1. Krishnatry R, Manjali JJ, Chinnaswamy G, Chatterjee A, Goda JS, Janu A, Sahu A, Jalali R, Gupta T (2021). Clinical approach to re-irradiation for recurrent diffuse intrinsic pontine glioma. Japanese Journal of Clinical Oncology.

2. Madhugiri V, Moiyadi AV, Shetty P, Gupta T, Epari S, Jalali R, Subeikshanan V, Dutt A, Sasidharan G, Kumar V, Ganesh C V Ramesh A, Prabhu A (2021). An analysis of the factors associated with long term survival in patients with glioblastoma. World Neurosurgery.

3. Mhatre O, Reddy BP, Patnaik C, Chakrabarty S, Ingle A, De A, Srivastava R (2021). pH-Responsive Delivery of Anti-Metastatic Niclosamide Using Mussel Inspired Polydopamine Nanoparticles, International Journal of Pharmaceutics.

4. Gupta T, Maitre M, Maitre P, Goda JS, Krishnatry R, Chatterjee A, Moiyadi A, Shetty P, Epari S, Sahay A, Patil V, Jalali R (2021). High-dose salvage re-irradiation for recurrent/progressive adult diffuse glioma: healing or hurting? Clinical and Translational Oncology.

5. Salunkhe S, Mishra SV, Nair J, Shah S, Gardi N, Thorat R, Sarkar D, Rajendra J, Kaur E, Dutt S (2021). Nuclear localization of p65 reverses therapy induced senescence. Journal of Cell Science.

Site of the Week

The BRCA Exchange aims to advance understanding of the genetic basis of breast, ovarian, pancreatic and other cancers by pooling data on BRCA1/2 genetic variants and corresponding clinical data from around the world.

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Interesting Reads

Angkasekwinai P, Dong C. IL-9-producing T cells: potential players in allergy and cancer. Nature Reviews Immunology. 21(1): 37-48, 2021.

Legends of Science
Rudolf Ludwig Carl Virchow Nirmal Kumar Dutta

Nirmal Kumar Dutta obtained MBBS from the University of Calcutta and obtained DSc (1964) from the Oxford University. His areas of specialization were physiology and pharmacology. He made important contributions to biological standardization of drugs and to the pharmacology of indigenous drugs. His method of development of experimental cholera in the infant rabbits, made possible the elucidation of many immunological and chemotherapeutic problems in cholera. He was the Director, Haffkine Institute, Mumbai, Deputy Director General, Indian Council of Medical Research, New Delhi. He was a member, Panel of Experts in Bacterial Diseases and Cholera (WHO), Drugs Technical Advisory Board, Government of India. Dutt was a recipient of Shanti Swarup Bhatnagar Prize (1965), The Watumull Award (1965).

Andreas Vesalius Bhola Nath Dhawan

Bhola Nath Dhawan, was an Neuropharmacologist. He obtained his MBBS (1954) and MD (1957) from King George’s Medical University, Luknow. He discovered the apomorphine stereotypy in pigeon. He elucidated the role of biogenic amines and opioid peptides. He also elucidated the role of neurotransmitters in the regulation of the blood brain barrier. He developed a simple procedure for transiently opening the blood brain barrier by administration of an intravenous bolus of hypertonic saline. His contributions includes discovery of 8 new drugs and a diagnostic kit. He has 70 International and National Patents to his credit. He was the recipient of TWAS Award in Basic Medical Sciences (1996).

Do You Know?

In 1890, The transfer of blood sera from individuals who had recovered from an infectious disease to individuals with ongoing infection with the same pathogen was first described for tetanus and diphtheria. This approach is still used today as a first-line therapy against arising viral infections for which few or no treatments exist.

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Cancer News
Mechanism that regulates anti-tumor activity of immune cells

03 February 2021, ScienceDaily

Researchers demonstrate why some ovarian cancer patients evolve better than others and suggest possible approaches to improve patient outcomes…

India Post, Mumbai Region, in collaboration with the Tata Memorial Centre, Mumbai releases a Special Cover on World Cancer Day

04 February 2021, Press Information Bureau Mumbai

India Post, Mumbai Region, in collaboration with the Tata Memorial Centre, Mumbai released a Special Cover on Cancer. This initiative taken on World Cancer Day- 2021 is aimed at spreading awareness about the disease and help people to imply the preventive measures of cancer in their lives…

ACTREC’s automated tool makes SARS-CoV-2 genome mutation analysis easy

06 February 2021, SCIENCE CHRONICLE

The IPD tool can automatically determine the abundance of SARS-CoV-2 genome sequences, carry out mutation analysis with respect to the Wuhan sequence and finally based on the mutations seen in each sample assign it to the respective phylogenetic clade...

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