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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 9th May 2022 Vol. No. 11; Issue No. 525

1. Mukherjee S, Maddalena M, Lü Y, Martinez S, Nataraj NB, Noronha A, Sinha S, Teng K, Cohen-Kaplan V, Ziv T, Arandkar S, Hassin O, Chatterjee R, Pirona AC, Shreberk-Shaked M, Gershoni A, Aylon Y, Elazar Z, Yarden Y, Schramek D, Oren M (2022). Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins. Proceedings of the National Academy of Sciences. 119(17):e2119644119

2. Pathiyil RK, Moiyadi AV, Shetty P, Singh V, Velayutham P (2022). Transopercular approach to resection of dominant hemisphere diffuse insular glioma using multimodal intraoperative strategy with awake mapping. Neurology India. 70: 520-3.

3. Vu MT, Shalkow J, Naik- Mathuria B, Qureshi S, Ozgediz D, Lakhoo K, Abdelhafeez H, On behalf of the Pan African Paediatric Surgery Association (PAPSA) and Global Initiative for Children’s Surgery (GICS) initiative (2022). Wilms’ tumor in low- and middle-income countries: survey of current practices, challenges, and priorities. Annals of Pediatric Surgery. 18:28.

4. Gupta N, Gupta D, Dixit J, Mehra N, Singh A, Krishnamurthy MN, Jyani G, Rajsekhar K, Kalaiyarasi JP, Roy PS, Malik PS, Mathew A, Malhotra P, Gupta S, Kumar L, Kataki A, Prinja S (2022). Cost effectiveness of Ribociclib and Palbociclib in the second-line treatment of hormone receptor-positive, HER2-negative metastatic breast cancer in post-menopausal Indian women. Applied Health Economics and Health Policy.

5. Mohanty P, Shetty D, Liehr T, Mrasek K, Khattry N (2022). Intrachromosomal amplification of BCR expressed as homogenously staining region (hsr) in a case of acute myeloid leukemia with myelodysplasia-related changes. International Journal of Laboratory Hematology.

Site of the Week

PHI-base (Pathogen Host Interactions) provides expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions.

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Interesting Reads

Larsen BD, Benada J, Yung PYK, Bell RAV, Pappas G, Urban V, Ahlskog JK, Kuo TT, Janscak P, Megeney LA, Elsässer SJ, Bartek J, Sørensen CS. Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress. Science. 376(6592):476-483, 2022.

Legends of Science
Debi Prasad Sarkar Debi Prasad Sarkar

Dr. Debi Prasad Sarkar, an immunologist, biochemist, and virologist obtained his Ph.D. from Kolkata University in 1986. Sarkar's research on Sendai virus is known to have resulted in the development of reconstituted viral envelopes containing only the fusion protein. This is reported to have assisted in a more efficient gene delivery in therapeutic use. He was the elected fellow of the National Academy of Sciences in 1996; the Indian Academy of Sciences in 2007, and the Indian National Science Academy in 2011. He was the recipient of the SS Bhatnagar Award in 1998; M. Sreenivasya Memorial Award of the Society of Biological Chemists in 2005.

Krishnaswamy Vijayraghavan Krishnaswamy Vijayraghavan

Krishnaswamy Vijayraghavan obtained his Ph.D. from the TIFR in 1983. His significant contribution is to developmental biology, genetics, and neurogenetics. His research focused on the principles and mechanisms that control the nervous system and muscles during development and how these neuromuscular systems direct locomotor behaviors. Dr. Vijayraghavan is a member of the Okinawa Institute of Science and Technology board of governors. He is an elected fellow of the Indian Academy of Sciences and a Foreign Associate of the US National Academy of Sciences. He received the SS Bhatnagar Award in 1998; Padma Shri in 2013; JC Bose award in 2006.

Upcoming Events
International School of Clinical Oncology Annual Congress (ISCO) 2022

12-13 May, 2022

At Marriott Cairo Hotel, Cairo, Egypt

4th International Conference on Cytokines in Cancer

19-24 May, 2022

At Chania, Crete, Greece

2nd Annual Conference on CNS Clinical Trials and Brain Metastases

12-13 August, 2022

At Toronto, Canada

Do You Know?

In 2001, researchers showed that diffuse large B-cell lymphoma, the most common form of non-Hodgkin lymphoma is actually two distinct diseases, each with its own generic profile.

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Cancer News
Uncovering warped protein interactions in cancer

04 May 2022, EurekAlert

The researchers have mapped altered protein-protein interactions resulting from mutations in major cancer-associated genes such as BRAF, AKT1, SPOP and SMAD4...

Tracing a cancer's family tree to its roots reveals how tumors grow

05 May 2022, MedicalXpress

In order to track cancer from its very beginning, the researchers developed an approach to simultaneously trigger cancer-causing mutations in cells and start recording the cells' history...

Breaking the shield that protects pancreatic cancer from immunotherapy

05 May 2022, ScienceDaily

Scar-like cells that make up a sizable portion of malignant pancreatic tumors and shield these cancers from immune attack are derived from mesothelial cells that line tissues and organs, a new study suggests...

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