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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 10th October 2022 Vol. No. 11; Issue No. 547

1. Chatterjee A, Asija S, Yadav S, Purwar R, Goda JS (2022). Clinical utility of CAR T cell therapy in brain tumors: Lessons learned from the past, current evidence and the future stakes. International Reviews of Immunology.

2. Shetty K, Yasaswi S, Dutt S, Yadav K (2022). Multifunctional nanocarriers for delivering siRNA and miRNA in glioblastoma therapy: advances in nanobiotechnology-based cancer therapy. 3Biotech.

3. Zodinpuii D, Pautu JL, Zothankima B, Khenglawt L, Lallawmzuali D, Lalmuanpuii R, zuali L, Ralte L, Muthukumaran RB, Varma AK, Zothanzama J, Kumar NS (2022). Breast cancer is significantly associated with cancers in the first and second degree relatives in ethnic Mizo Mongoloid population, Northeast India. National Journal of Community Medicine. 13(9):606-611.

4. Mishra SK, De A (2022). Photothermal Therapy (PTT) is an effective treatment measure against solid tumors which fails to respond conventional chemo/radiation therapies in clinic. Biomaterials Advances.

Asim Sandeep Joshi. 2022. Understanding the complexities of human lung cancer genome. (LIFE09201504015) (Guide: Dr Amit Dutt)

Site of the Week

Mechanism and Catalytic Site Atlas is a database of enzyme reaction mechanisms. It provides annotation on the protein, catalytic residues, cofactors, and the reaction mechanisms of hundreds of enzymes.

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Interesting Reads

Sandlin CW, Gu S, Xu J, Deshpande C, Feldman MD, Good MC. Epithelial cell size dysregulation in human lung adenocarcinoma. PLoS One, 2022. 17(10): e0274091

Legends of Science
Raghunath Sahai Vasudeva Raghunath Sahai Vasudeva

Raghunath Sahai Vasudeva obtained his Ph.D. from the University of London, the UK, in 1930. His research included diverse fields like plant virology, mycology, and fungal pathology. His significant contribution was the crop diseases, diseases of the Apple and onion, root rot diseases of cotton, cowpea, and tomato. He was instrumental in starting Plant Virus Research across various states and universities. He was Joint Director, Division of Mycology and Pathology, Indian Agricultural Research Institute, New Delhi. Dr. Vasudeva was Agricultural Advisor to FAO in Togo in 1962, in Cuba and Rome till 1969. He was elected twice as President of the Indian Phytopathological Society in 1953 and 1958. He was a Fellow of the National Institute of Sciences in India and an Honorary Fellow of the Indian Phytopathological Society.

Surath Kumar Mukherjee Surath Kumar Mukherjee

Surath Kumar Mukherjee received his DPhil from the University of Calcutta in 1957. He specialized in endocrinology, metabolic disorders, and toxicology. He discovered a novel synthetic hypoglycemic compound. He established a direct relationship between obesity and diabetes mellitus in CF strain rats. His significant contribution was in advancing research on drug toxicology. He was a UNIDO consultant on toxicology. He was the recipient of the PP Surya Kumar Prize. He was a Fellow National Academy of Medical Sciences.

Upcoming Events
4th International Symposium on Mechanobiology

06-09 November, 2022

At Sydney, Australia.

5th World Congress on Clinical Surgery and Anesthesia

21-22 November, 2022

At London, UK.

Development and 3D Modeling of the Human Brain

07-09 December, 2022

At Cold Spring Harbor, NY, US.

Do You Know?

In 1975, Köhler and Milstein developed methods for producing antibodies by fusing cultured myeloma cells with normal B cells from immunized mice.

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Cancer News
New gene target for aggressive lung cancer discovered

05 October 2022, EurekAlert

The gene the scientists discovered is essential for this tumor subtype to thrive, Wang said, based on genome-wide CRISPR screening.The scientists’ findings can potentially serve as a biomarker to identify this subtype of small-cell lung cancer at earlier stages...

Sodium thiosulfate approved to reduce chemo-related hearing loss in children with cancer

06 October 2022, National Cancer Institute

The Food and Drug Administration (FDA) has approved sodium thiosulfate anhydrous (Pedmark) to reduce the risk of hearing loss among infants, children, and adolescents with cancer who receive the chemotherapy drug cisplatin...

Study shows novel agent can overcome immune dysfunction in cancer

06 October 2022, MedicalXpress

The team focused on the concept of differentiation, which enables cells to mature. Since MDSCs comprise populations of immature cell types, the team tested whether this agent drives MDSC maturation as a means to reduce their burden...

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