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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 14th November 2022 Vol. No. 11; Issue No. 552

1. Madhugiri VS, Venkatesan S, Dutt A, Moiyadi AV, Shetty P, Gupta T, Epari S, Jalali R, Sasidharan GM, Kumar VRR, Ganesh CVS, Ramesh AS, Prabhu AS, Dutt AK (2022). An analysis of eosinophil and basophil based indices in patients with glioblastoma and their correlation with survival. World Neurosurgery.

2. Deshpande G, Menon S, Rekhi B. Mittal N, Maheshwari A, Shylashree TS, Chopra S, Gurram L, Ghosh J, Gulia S, Gupta S, Deodhar K (2022). Extramammary Paget’s disease of vulva: A clinicopathological case series of a rare disease. Indian Journal of Gynecologic Oncology. 20:61.

3. Biswas C, Jain K, Velayutham P, Singh V, Shetty P, Moiyadi A (2022). Awake mapping unmasks functional substrates guiding safe radical resection of “Nondominant” right insular glioma using a transopercular approach. Neurology India 70(5):1808-12

4. Panda PK, Gupta T, Jalali R (2022). A practice pilot survey on the current use of corticosteroid therapy in brain tumor patients. Neurology India. 70(5):1896-900

5. Dubey S, Mishra N, Goswami N, Siddiqui MQ, Varma A (2022). Multimodal approach to characterize the tetrameric form of human PML-RBCC domain and ATO-mediated conformational changes. International Journal of Biogical Macromolecules. 223: 468-478.

6. Sriram H, Kunjachan F, Khanka T, Gawai S, Ghogale S, Deshpande N, Girase K, Patil J, Chatterjee G, Rajpal S, Patkar NV, Bagal B, Jain H, Sengar M, Hasan SK, Khattry N, Subramanian PG, Gujral S, Tembhare PR (2022). Expression levels and patterns of B-cell maturation antigen in newly diagnosed and relapsed multiple myeloma patients from Indian subcontinent. Cytometry B Clinical Cytometry

7. Gulia S, Kannan S, Gupta S (2022). Maintenance therapy with a poly (ADP-ribose) polymerase inhibitor in patients with newly diagnosed advanced epithelial ovarian cancer: Updated individual patient data and trial-level meta-analysis. ESMO Open. 7(6):1006.

Site of the Week

The Dinucleotide Property Database is designed to collect and analyse thermodynamic, structural and other dinucleotide properties.

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Interesting Reads

Núñez KG, Sandow T, Lakey MA, Fort D, Cohen AJ, Thevenot PT. Distinct Gene Expression Profiles in Viable Hepatocellular Carcinoma Treated With Liver-Directed Therapy. Front Oncol. 12: 809860, 2022.

Legends of Science
Arun Kumar Sharma Arun Kumar Sharma

Arun Kumar Sharma secured his PhD from the University of Kolkata in 1955. He made significant contribution in the areas of studies on the physical and chemical nature of chromosomes. He is credited with developing new research techniques for the study of chromosome structure of plants. He is the elected fellow of the Indian National Science Academy; Indian Academy of Sciences and the National Academy of Sciences, India. He is the recipient of Om Prakash Bhasin award in 1992; the S S Bhatnagar award in 1976; Padma Bhushan award in 1983.

Ardhendu Sekhar Mukherjee Ardhendu Sekhar Mukherjee

Ardhendu Sekhar Mukherjee obtained his PhD from the University of California in 1964. His significant contribution was in Drosophila genetics. He discovered the rapid method of scintillation autoradiography and worked on the role of hormones in development and carcinogenesis. Dr. Mukherjee was the Fellow, Royal Microscopical Society, London; Member, All India Cell Biology Society and Society for Cytology and Genetics.

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Do You Know?

In 2005, two landmark studies demonstrate that human cancer cells with mutations in the tumour-suppressor genes BRCA1 and BRCA2 are sensitive to poly(ADP–ribose) polymerase inhibitors.

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Cancer News
CRISPR cancer trial success paves the way for personalized treatments

10 November 2022, Nature

A small clinical trial has shown that researchers can use CRISPR gene editing to alter immune cells so that they will recognize mutated proteins specific to a person’s tumours...

Experimental cancer vaccine shows promise in animal studies

10 November 2022, National Institute of Health

Researchers found that intravenous (IV) administration of the vaccine boosted the number of cytotoxic T cells capable of infiltrating and attacking tumor cells and engaged the innate immune system by inducing type I interferon...

'CAR pooling' screens identify most effective cancer immunotherapy cells

10 November 2022, MedicalXpress

Researchers have developed a new method for comparing massive numbers of these CAR-T cells, each with slightly different molecular features, to determine which is most effective and long-lasting against cancer...

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