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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 15 May 2023 Vol. No. 12; Issue No. 578

1. Moiyadi A, Jain K, Shetty P, Singh VK, Radhakrishnan K, Rane P, Velayutham P (2023). Baseline neurocognitive dysfunction is ubiquitous in intrinsic brain tumors– results from a large Indian cohort of patients and analysis of factors associated with domain-specific dysfunction. World Neurosurgery: X

2. Im SA, Gennari A, Park YH, Kim JH, Jiang ZF, Gupta S, Fadjari TH, Tamura K, Mastura MY, Abesamis-Tiambeng MLT, Lim EH, Lin CH, Sookprasert A, Parinyanitikul N, Tseng LM, Lee SC, Caguioa P, Singh M, Naito Y, Hukom RA, Smruti BK, Wang SS, Kim SB, Lee KH, Ahn HK, Peters S, Kim TW, Yoshino T, Pentheroudakis G, Curigliano G, Harbeck N (2023). Pan-Asian adapted ESMO Clinical Practice Guidelines for the diagnosis, staging and treatment of patients with metastatic breast cancer. ESMO Open. 8(3): 101541.

3. Deshpande A, Varghese R, Pal K (2023). On-demand male contraceptives: gazing at the long road ahead. International Journal of Impotence Research.

4. Mittal P, Chopra S, Kamrava M, Vashistha R, Konrad S, Senapati S, Pradhan S, Reddy VA, Sharma DN, Engineer R, Sarin R, Budrukkar A, Ghoshal S, Shrivastava SK, Agarwal JP, Sturdza AE (2023). A randomized, controlled trial of a clinical pharmacist intervention to improve inappropriate prescribing in elderly outpatients with polypharmacy. Brachytherapy.

5. Srinivasan S, Ramanathan S, Kumar S, Peyam S, Radhakrishnan V (2023). Prevalence and prognostic significance of IKZF1 deletion in paediatric acute lymphoblastic leukemia: A systematic review and meta-analysis. Annals of Hematology.

6. Bindal A, Mittal P, Shinghal A, Scaria L, Prajapati K, Swamidas J, Gurram L, Berger D, Sturdza A, Chopra S (2023). Sigmoid dose accumulation and reporting for multifractionated brachytherapy for cervical cancer: Methodological development of sigmoid points through virtual endoscopic method. Brachytherapy. 22(3):325-333.

Site of the Week

PROXiMATE is a mutant protein-protein interaction kinetics and thermodynamics database which contains thermodynamic data for mutant protein heterodimer complexes.

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Interesting Reads

Segura-Collar B, Hiller-Vallina S, de Dios O, Caamaño-Moreno M, Mondejar-Ruescas L, Sepulveda-Sanchez JM, Gargini R. Advanced immunotherapies for glioblastoma: tumor neoantigen vaccines in combination with immunomodulators. Acta Neuropathol Commun. 11(1): 79, 2023.

Legends of Science
Pran Nath Mehra Pran Nath Mehra

Pran Nath Mehra obtained his DSc from the University of Panjab in 1942. He specialized in cytology, the morphology of bryophytes and vascular plants, medicinal plants, tissue culture and morphogenesis. He made extensive contributions to the phyletic evolution of grasses, the distribution of Prodocarpean flora, and the concept of Gondwanaland. Dr Mehra is the recipient of the Padmashri (1972); Birbal Sahni Gold Medal (1968), and Gunner Erdtman International Gold Medal (1975). He was a member of the INSA Council (1969-70). He was a fellow of the National Academy of Sciences, Allahabad; Indian Botanical Society; Indian Palynological Society; Indian Society of Pharmacognosy.

Kariamanikkam Srinivasa Krishnan Kariamanikkam Srinivasa Krishnan

Kariamanikkam Srinivasa Krishnan obtained DSc from the University of Madras in 1920. His main research topic was the Experimental study of the scattering of light in a large number of liquids and its theoretical interpretations. He developed an elegant and precise experimental technique to measure the magnetic anisotropy of diamagnetic and paramagnetic crystals. He was the elected Fellow of the Royal Society (1940); Padma Bhushan (1954). He was the first recipient of the S S Bhatnagar Award(1958).

Upcoming Events
RNA Polymerase Activity and Regulation by Associated Factors

10-11 June, 2023

At Southern New Hampshire University, Manchester, United States.

Molecular Devices: Development, Application and Opportunity

17-18 June, 2023

At Colby-Sawyer College, New London, United States.

Advances In Brain Tumor Research and Therapy

25-30 June, 2023

At Bryant University, Smithfield, United States.

Do You Know?

In 1996, Matthew Scott discovered a gene responsible for basal cell carcinoma, the most common human cancer.

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Cancer News
Proton therapy comes to public sector now

12 May 2023, Times of India

Prime Minister Narendra Modi virtually inaugurated the much awaited proton beam therapy facility at the Tata Memorial Centre’s Kharghar campus. The facility, the first in a public setup in India, will provide the cutting edge proton beam treatment for free to 60% of the patients needing it. The remaining 40% will pay a subsidised rate almost a third of the Rs 30-lakh tag in the private sector...

Combination therapy outperforms chemotherapy in clinical trial for patients with chronic lymphocytic leukemia

10 May 2023, MedicalXpress

The researchers learned from previous studies that the drug venetoclax effectively inhibits the Bcl-2 protein. Cells in the blood do still die, but crucially, not during the pit stop in the lymph node...

Vaccine boosts T cells that target pancreatic tumours

10 May 2023, Nature

Efforts to tackle pancreatic cancer by harnessing immune cells have had limited success. A clinical trial reports promising results from testing a personalized approach to boosting immune responses to such tumours...

2023 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)