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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 1st August 2022 Vol. No. 11; Issue No. 537

1. Mukherjee S, Sakpal A, Mehrotra M, Phadte P, Rekhi B, Ray P (2022). Homo and heterotypic cellular cross-talk in epithelial ovarian cancer impart pro-tumorigenic properties through differential activation of the Notch3 pathway. Cancers. 14(14): 3365.

2. Dhawan A, Lokras A, Joshi G, Marwah M, Venkatraman M, Mohanty B, Darshan K, Chaudhaty P, Warawdekar U, Saraf M, Nagarsenkar M (2022). Polysaccharide and monosaccharide guided liver delivery of Sorafenib Tosylate –a nano-strategic approach and comparative assessment of hepatospecificity. International Journal of Pharmaceutics.

3. Rajak J, Tambe M, D'Silva SZ, Singh M (2022). Identification of the novel HLA-A*68:175:02 and -A*68:287 alleles in Indian individuals. HLA.

4. Gohil D, Panigrahi GC, Gupta SK, Gandhi KA, Gera P, Chavan P, Sharma D, Sandur S, Gota V (2022). Acute and sub-acute oral toxicity assessment of 5-hydroxy-1,4-naphthoquinone in mice. Drug and Chemical Toxicology.

5. Uthale A, Anatram A, Sulkshane P, Degani M, Teni T (2022). Identification of bicyclic compounds that act as dual inhibitors of Bcl-2 and Mcl-1. Molecular Diversity.

Site of the Week

Datanator is a free and open toolkit for discovering the data needed to build, calibrate, and validate mechanistic models of cells.

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Interesting Reads

Pascarella G, Hon CC, Hashimoto K, Busch A, Luginbühl J, Parr C, Hin Yip W, Abe K, Kratz A, Bonetti A, Agostini F, Severin J, Murayama S, Suzuki Y, Gustincich S, Frith M, Carninci P. Recombination of repeat elements generates somatic complexity in human genomes. Cell, 2022.

Legends of Science
Sasanka Chandra Bhattacharya Sasanka Chandra Bhattacharya

Sasanka Chandra Bhattacharyya obtained his Ph.D. from the University of Dacca in 1944. He developed synthetic approaches for prostaglandins and new analytical reagents. He also isolated and determined the structure of over a hundred complex natural products like terpenoids and coumarins. Dr. Bhattacharya was the recipient of the S S Bhatnagar Prize in 1962 and; the Dr. B C Roy National Award in 1978. He was a Fellow of the Indian Academy of Sciences, Bangalore, and the Indian Chemical Society.

Tathamangalam Ananthanarayanan Venkitasubramanian T A Venkitasubramanian

Tathamangam A Venkitasubramanian secured his Ph.D. from the University of Madras in 1951. He was the Head of the Biochemistry department at Vallabhai Patel Chest Institute, New Delhi. He has done pioneering research on the biochemistry of tubercle bacilli and also on Aspergillus parasiticus, a type of mold that produces aflatoxin. His research helped to understand intermediary metabolism in cultured mycobacteria and experimental tuberculosis models. He was awarded Shanti Swarup Bhatnagar Prize in 1968.

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02-04 December, 2022

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Do You Know?

1933, R. Shope discovered cottontail rabbit papillomavirus or Shope papillomavirus, the first mammalian DNA tumor virus.

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Cancer News
Frequent aspirin use shows promise for preventing ovarian cancer in individuals at higher risk

26 July 2022, EurekAlert

Researchers found that almost daily aspirin use was associated with a 13% reduction in ovarian cancer risk...

Akt protein boosts cancer metabolism through a two-pronged attack

27 July 2022, Nature

Mutated forms of the protein Akt can be central drivers of cancer metabolism. A mechanism by which Akt promotes synthesis of the metabolic molecule coenzyme A broadens our understanding of the protein’s activity...

Gene that causes deadliest brain tumor also causes childhood cancers, new research shows

28 July 2022, MedicalXpress

The new discovery may open the door to the first targeted treatments for two types of rhabdomyosarcoma, a cancer of the soft tissue that primarily strikes young children...

2022 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)