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Science Sparks @ ACTREC
Date Image 26 June 2023 Vol. No. 12; Issue No. 584

1. Ghantasala S, Bhat A, Agarwal U, Biswas D, Bhattarai P, Epari S, Moiyadi A, Srivastava S (2023). Deep Proteome investigation of high-grade gliomas reveals heterogeneity driving differential metabolism of 5-Aminolevulinic acid. Neuro-Oncology Advances.

2. Singh A, Shetty D, Patil J, More M, Chatterjee G, Rajpal S, Patkar NV, Subramanian PG, Gujral S, Tembhare PR (2023). Acute basophilic leukemia in a patient with down syndrome: A case report and review of literature. International Journal of Laboratory Hematology.

3. Dutta RP, Kumar R, Tembhare PR, Bagal B, Swain RK, Hasan SK (2023). Targeting transcriptional kinase of CDK7 halts proliferation of multiple myeloma cells by modulating the function of canonical NF-kB pathway and cell cycle regulatory proteins. Translational Oncology. 35:101729.

4. Rekhi B, Dave V, Butle A, Dutt A (2023). Utility of immunohistochemical expression of H3.3K36M and DOG1 in the diagnosis of chondroblastomas: An experience from a tertiary cancer referral center. Annals of Diagnostic Pathology. 66: 152174.

Site of the Week

PDBsum is a pictorial database that provides an at-a-glance overview of the contents of each 3D structure deposited in the Protein Data Bank (PDB)

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Interesting Reads

Schmidt ME, Chong M, Klassen O, Wiskemann J, Steindorf K. Longitudinal associations of bioelectrical phase angle and fatigue in breast cancer patients. Int J Cancer. 2023.

Legends of Science
Kandala Venkata Ramana Chary Kandala Venkata Ramana Chary

Kandala Venkata Ramana Chary obtained his PhD from Osmania University, Hyderabad, in 1983. His primary research areas included Structural Biology, Molecular Biophysics and Biological chemistry. He showed the capability of solving complete 3D solution structures of proteins by NMR. He developed rapid NMR methodologies and proposed new NMR pulse sequences. He is an elected member of the Indian National Science Academy, New Delhi (2012) and an elected member of the National Academy of Sciences (2000).

Uma Prasanna Basu Uma Prasanna Basu

Uma Prasanna Basu obtained his DSc from the University of Kolkata in 1935. He specialized in organic chemistry and natural products. He developed antimalarials with the synthesis of many new acridine derivatives. With the help of Guareschi's synthesis of pyridines, he synthesized some B-hexahydroisoquinolines. He won the Nagarjuna Prize. He was the President Indian Science Congress. He was a member Indian Chemical Society, the Institution of Chemists, The Indian Association for the Cultivation of Science and the Asiatic Society.

Upcoming Events
Molecular Analysis for Precision Oncology Congress 2023

04-06 October, 2023

At Paris, France.

ICGA (Indian Cancer Genome Atlas) Conference 2023

06-08 October, 2023

At IISER, Pune.

ESMO Asia Congress 2023

01-03 December, 2023

At Singapore.

Do You Know?

In 1994, David G.I. Kingston reported results of the drug Taxol as an effective second-line therapy for advanced breast cancer.

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Cancer News
Study gives new insight into how cancer metastasizes to the brain

20 June 2023, MedicalXpress

Using brain metastasis mouse models, researchers showed that when the astrocytes were exposed to cancer cells, they began to activate type I interferon pathways. Type I interferon, the cytokines associated with regulating inflammation, have been shown to have to anti-tumor effects...

Researchers identify new biomarkers of the most frequent lung cancer

20 June 2023, EurekAlert

The new methodology is based on digitized images of patient biopsies stained with a dye called picrosirius red (PSR) and imaged with polarized light...

FDA approves Talzenna-Xtandi combo for subset of patients with prostate cancer

21 June 2023, Cure

The Food and Drug Administration (FDA) approved Talzenna (talazoparib) with Xtandi (enzalutamide) for the treatment of patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer...

2023 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)