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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 27 February 2023 Vol. No. 12; Issue No. 567

1. Thomas M, Agarwal V, DeSouza A, Joshi R, Mali M, Panhale K, Salvi OK, Ambulkar R, Shrikhande S, Saklani A(2023). Enhanced recovery pathway in open and minimally invasive colorectal cancer surgery: a prospective study on feasibility, compliance, and outcomes in a high-volume resource limited tertiary cancer center. Langenbeck's Archives of Surgery 408(1):99.

2. Shruti T, Khanna D, Khan A, Dandpat A, Tiwari M, Singh AG, Mishra A, Shetty A, Birur P, Chaturvedi P (2023). Status and determinants of early detection of oral premalignant and malignant lesions in India. Cancer Control.

3. Joshi S, Chougle Q, Noronha J, Hawaldar R, Nair N, Vanmali V, Parmar V, Thakkar P, Chitkara G, Shet T, Badwe R. Determinants of pathological complete response to neoadjuvant chemotherapy in breast cancer: A single institution experience. Indian Journal of Cancer.

4. Budukh A, Pradhan S, Singh VB, Khanna D, Bagal SS, Chakravarti PS, Sharma AN, Vishwakarma RK, Shinde SS, Khargekar NC, Chaturvedi P, Dikshit RP, Shukla VK, Badwe R (2023). Cancer pattern in Varanasi district from Uttar Pradesh state of India, a foundation for cancer control based on the first report of the population-based cancer registry. Indian Journal of Cancer.

5. Chakraborty S, Shenoy PS, Mehrotra M, Phadte P, Singh P, Rekhi B, Ray P. Through the looking Glass: Updated insights on ovarian cancer diagnostics. Diagnostics. 13(4): 713.

6. Patil V, Noronha V, Menon N, Mathrudev V, Bhattacharjee A, Nawale K, Parekh D, Banavali S, Prabhash K (2023). Metronomic adjuvant chemotherapy evaluation in locally advanced head and neck cancers post radical chemoradiation–a randomised trial. Lancet Regional Health - Southeast Asia.

Site of the Week

FindPept identifies peptides that result from unspecific cleavage of proteins from their experimental masses, taking into account artefactual chemical modifications, post-translational modifications (PTM) and protease autolytic cleavage.

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Interesting Reads

Bhardwaj M, Lee JJ, Versace AM, Harper SL, Goldman AR, Crissey MAS, Jain V, Singh MP, Vernon M, Aplin AE, Lee S, Morita M, Winkler JD, Liu Q, Speicher DW, Amaravadi RK. Lysosomal lipid peroxidation regulates tumor immunity. J Clin Invest. 2023.

Legends of Science
Tangirala Ramasarma Tangirala Ramasarma

Tangirala Ramasarma received his PhD from Mumbai University in 1956. His research topics were Mitochondria and cholesterol biogenesis. He worked on environmental stress and biochemical adaptation, focusing on enzyme regulation and mitochondrial function. He was an elected Fellow of the Indian National Science Academy in 1989.

Rajat De Rajat De

Rajat De obtained his PhD from the Banaras Hindu University in 1952. His area of research was rainfed agronomy, especially in situ moisture conservation by using soil mulches and foliar application of transpiration suppressants, which acted as heat reflectant or stomata regulator and increased water use efficiency. He introduced the concept of growing four food crops in a year resorting to relay cropping on the same piece of land. He was the Gold medalist of the Indian Society of Agronomy. He received the CIMMYT award from International Maize and Wheat Improvement Centre, Mexico, for his contribution to wheat research. He was the Fellow of the National Academy of Agricultural Sciences, New Delhi.

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Do You Know?

In 1966, Wattenberg introduced the term “chemoprophylaxis” in a landmark review of experimental inhibition of chemically induced animal carcinogenesis that appeared in the journal Cancer Research.

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Cancer News
Immunotherapy-resistant cancer patients lack critical immune cells

21 February 2023, Genetic Engineering and Biotechnology News

The findings suggests that a supplementary therapy designed to increase the number or activity of CD5+ dendritic cells potentially could extend the lifesaving benefits of immunotherapy to more cancer patients...

New promising targeted drug for a rare leukemia

23 February 2023, MedicalXpress

Among the more than 500 agents analyzed, BCL-XL protein inhibitors in particular were effective in killing cancer cells isolated from these types of leukemia. The BCL-XL protein has a similar function of preventing cells from being driven to programmed cell death as BCL-2, the target of venetoclax...

Predicting the likelihood of kidney cancer recurrence by looking at DNA mutations

24 February 2023, News Medical

The Researchers study the changes in the DNA of more than 900 kidney cancer samples and identified four groups of patients based on the mutations in 12 specific genes within the DNA. The team also looked at whether the cancer had recurred in each of these patients...

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