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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 28 August 2023 Vol. No. 12; Issue No. 593

1. Nag S, Dikshit R, Desai S, Mane A, Mhatre S, Neve R, Gurav M, Bhosale N, Perumal P, Kembhavi Y, Jethwa D, Badwe R, Gupta S (2023). Risk factors for the development of triple-negative breast cancer versus non-triple-negative breast cancer: a case-control study. Scientific Reports. 13(1): 13551.

2. Rajendra A, Sengar M, Bonda VNA, Jain H, Nayak L, Thorat J, Shet T, Epari S, Laskar S, Aggarwal A, Rangarajan V, Gujral S, Bagal B, Kakoti S, Salvi O (2023). Outcomes and prognostic factors of patients with Extranodal NK T cell lymphoma (ENKTL). Leukemia Lymphoma.

Chougule A, Chandrani P, Noronha V, Pange P, Kale S, Nikam A, Nambiar K, Marchande D, Durve A, Gupta V, Jagtap V, Tiwrekar P, Menon N, Joshi A, Kaushal R, Pai T, Patil V, Dutt A, Banavali S, Prabhash K (2023). Real world evidence of EGFR targeted therapy in non-small cell lung cancer– a brief report of decade long single centre experience. JTO Clinical and Research Reports.

Anagha Acharekar. 2023. : Understanding the role of radiation induced cell-cell fusion in glioblastoma. (LIFE09201504020) (Guide: Dr. Shilpee Dutt)

Site of the Week

BloodChip database provides a user-friendly exploration and visualization of transcription factor (TF) binding sites in human CD34+ and leukemia cells produced by TF ChIP-Seq platform.

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Interesting Reads

Li J, Hubisz MJ, Earlie EM, Duran MA, Hong C, Varela AA, Lettera E, Deyell M, Tavora B, Havel JJ, Phyu SM, Amin AD, Budre K, Kamiya E, Cavallo JA, Garris C, Powell S, Reis-Filho JS, Wen H, Bettigole S, Khan AJ, Izar B, Parkes EE, Laughney AM, Bakhoum SF. Non-cell-autonomous cancer progression from chromosomal instability. Nature. 2023.

Video of the Week
Development of Systemic Therapy in Head and Neck Cancer in Indian Context
Upcoming Events
Hallmarks of Skin Cancer Conference 2023

22-23 October, 2023

At German Cancer Research Center (DKFZ) Heidelberg, Germany.

11th International Conference and Preconference Workshop of Laboratory Animal Scientists’ Association (LASA)

06-08 November, 2023

At J N Tata Auditorium, National Science Seminar Complex, Indian Institute of Science, Bengaluru.

9th International Conference on Mechanics of Biomaterials and Tissues

16-20 December, 2023

At Waikoloa Beach, Hawaii, USA.

Do You Know?

In 2009 researchers described how a single small intestinal stem cell could expand to crypt-villus organoids in culture without a mesenchymal niche.

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Cancer News
Engaging people with low-grade glioma in cancer research

24 August 2023, National Cancer Institute

The study, which is part of the Cancer Moonshot initiative, aims to improve the care of people with low-grade glioma by understanding more about the biology of the disease. To achieve this goal, the study is exploring new ways to involve participants in cancer research...

Gene therapy study identifies potential new treatment for liver cancer

24 August 2023, MedicalXpress

Gene therapy that induces the body to create microRNA-22 (miR-22), a naturally occurring molecule, successfully treated mice with hepatocellular carcinoma, the most common form of liver cancer...

New research sheds light on role of KRAS mutations in pancreatic cancer

24 August 2023, News-Medical

This study demonstrated that oncogenic KRAS epigenetically blocks expression of the Fas protein, silencing the pathway and allowing cancer cells to avoid an anti-tumor immune response. Suppressing KRAS led to complete tumor regression and significantly improved survival in these models, suggesting the potential for KRAS inhibition to improve immunotherapy responses and prevent relapse...

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