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Science Sparks @ ACTREC
Date Image 02 January 2022 Vol. No. 12; Issue No. 559

1. Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Godbole M, Dutt A (2022). Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer. Breast Cancer Research. 24(1): 97.

2. Ghosh Laskar S, Chaukar D, Deshpande M, Chatterjee A, Sinha S, Chakraborty S, Agarwal JP, Gupta T, Budrukkar A, Murthy V, Pai P, Chaturvedi P, Pantvaidya G, Deshmukh A, Nair D, Nair S, Prabhash K, Swain M, Kumar A, Noronha V, Patil V, Joshi A, D'Cruz A (2022). Oral Cavity Adjuvant Therapy (OCAT) -A phase III, randomized controlled trial of surgery followed by conventional RT (5 fr/wk) vs concurrent CT-RT vs accelerated RT (6fr/wk) in locally advanced, resectable, squamous cell carcinoma of oral cavity. European Journal of Cancer.

3. Sahu A, Patnam N, Goda JS, Epari S, Sahay A, Mathew R, Choudhari A, Desai S, Dasgupta A, Chatterjee A, Pratishad P, Shetty P, Moiyadi A, Gupta T (2023). Multiparametric magnetic resonance imaging correlates of isocitrate dehydrogenase mutation in WHO high-Grade astrocytomas. Journal of Personalized Medicine. 13(1): 72.

4. Dilli Batcha JS, Raju AP, Matcha S, Raj SEA, Udupa KS, Gota, V, Mallayasamy S (2023). Factors influencing pharmacokinetics of tamoxifen in breast cancer patients: A systematic review of population pharmacokinetic models. Biology. 12:51.

5. Spohn S, Draulans C, Kishan A, Spratt D, Ross A, Maurer T, Tilki D, Berlin A, Blanchard P, Collins S, Bronsert P, Chen R, Pra A, Meerleer G, Eade T, Haustermans K, Hölscher T, Höcht S, Ghadjar P, Davicioni E, Heck M, Kerkmeijer L, Kirste S, Tselis N, Tran P, Pinkawa M, Pommier P, Deltas C, Schmidt-Hegemann N, Wiegel T, Zilli T, Tree A, Qiu X, Murthy V, Epstein J, Graztke C, Gao X, Grosu A, Kamran S, Zamboglou C (2022). Genomic classifiers in personalized prostate cancer radiotherapy approaches – A systematic review and future perspectives based on international consensus. International Journal of Radiation Oncology, Biology Physics.

Book Chapter
Dahara R, Jain B, Bhattacharyya D (2023). Visualizing Reversible Cisternal Stacking in Budding Yeast Pichia pastoris. In: Wang Y, Lupashin VV, Graham TR. (Eds) Golgi. Methods in Molecular Biology, vol 2557. New York, Humana. (ISBN: 978-1-0716-2638-2)

Site of the Week

BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats

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Interesting Reads

Bhatia HS, Brunner AD, Öztürk F, Kapoor S, Rong Z, Mai H, Thielert M, Ali M, Al-Maskari R, Paetzold JC, Kofler F, Todorov MI, Molbay M, Kolabas ZI, Negwer M, Hoeher L, Steinke H, Dima A, Gupta B, Kaltenecker D, Caliskan ÖS, Brandt D, Krahmer N, Müller S, Lichtenthaler SF, Hellal F, Bechmann I, Menze B, Theis F, Mann M, Ertürk A. Spatial proteomics in three-dimensional intact specimens. Cell 185(26):5040-5058.e19, 2022.

Legends of Science
Rudrendra Kumar Pal Rudrendra Kumar Pal

Rudrendra Kumar Pal obtained his DSc from the University of Edinburgh, UK, in 1931. His primary research included the Effects of vitamins on the thyroid and suprarenals, the vagotropic action of insulin on the heart, the cardiotonic action of insulin with transfusion of glucose solution, and the synthesis of two new oral hypoglycaemic drugs. He was a member of the INSA Council. He won the ND Agarwalla Prize from the University of Delhi Golden Jubilee Plaque by INSA. He was elected Fellow of the Royal Society of Edinburgh, President Asiatic Society.

Shyamsunderlal Pradhan Shyamsunderlal Pradhan

Shyamsunderlal Pradhan received his DSc from the University of Lucknow in 1938 and PhD from the University of London, UK, in 1948. He generalized the dynamics of temperature effect on insect development. He invented a biometer and standardized techniques for population study. His other research topics included the biotic theory of the locust cycle, the effect of temperature on the susceptibility of insects to insecticides, the impact of particle size on the toxicity of insecticides, the mode of action of DDT, neem as an insect repellent, and ecological manipulation for safe storage of food grains. Dr Pradhan was the recipient of the Hari Om Ashram Trust Award. He was elected Fellow of the Royal Entomological Society and Entomological Society of India and remained President for four terms.

Upcoming Events
42nd Annual Conference of the Indian Association for Cancer Research

12-16 January, 2023

At Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai.

4th Annual Congress of Immuno Oncology Society of India

20-22 January, 2023

At Mahatma Gandhi Medical College & Hospital, Jaipur.

45th All India Cell Biology Conference and International Symposium of Biology of Development and Disease

20-22 January, 2023

At Banaras Hindu Univerisity, Varanasi.

Do You Know?

In 1895, William Coley, a surgeon at Memorial Sloan Kettering, pioneered the first nonsurgical treatment of cancer through an early form of immunotherapy. He treated sarcoma with the toxins of a bacterial skin infection to rally the body’s natural defenses against cancer.

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Cancer News
NCI clinical trial leads to atezolizumab approval for advanced alveolar soft part sarcoma

28 December 2022, National Cancer Institute

Atezolizumab is an anti-PD-L1 immune checkpoint inhibitor that works by helping the immune system respond more strongly to cancer...

High fat ketogenic diet envisioned as potential life-saving therapy to combat low platelets in cancer patients

29 December 2022, MedicalXpress

A high-fat diet may combat low platelet counts in the blood caused by chemotherapy, according to preliminary research, which suggests that a ketogenic eating plan may be a nontoxic, low-cost and high-benefit addition to cancer therapy...

Yoga to mitigate chances of Recurrence & Death in Breast Cancer: Study

30 December 2022, NewsOnAIR

The study conducted by Tata Memorial Centre( TMC) is the first one where the long term benefits in quality of life have been noted with the addition of yoga for women undergoing treatment for breast cancer...

2023 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)