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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 31st October 2022 Vol. No. 11; Issue No. 550

1. Chatterjee G, Patkar N (2022). United we stand, divided we fall. Multicentre standardization of measurable residual disease assessment in acute leukaemia is the way forward. British Journal of Haematology.

2. Rajput N, Gholap D, Mhatre S, Dikshit R (2022). Epidemiological Review: Esophagus squamous cell carcinoma in India. Indian Journal of Medical and Paediatric Oncology. 43(5): 393-403.

3. Wadasadawala T, Kumar A, Laskar S, Mokal S, Kapoor R, Das A, Pradhan S, Pujari L, Mahantshetty U, Vadgaonkar R, Agarwal J (2022). A longitudinal study to Reexamine the mental health impact on radiation oncology health care workers with the launch of COVID-19 vaccination strategies in India. Indian Journal of Medical and Paediatric Oncology. 415-423.

4. Poon D, Yuan J, Yang B, Kerkmeijer L, Kishan A, Murthy V, Zapaetero A, Wong O (2022). Magnetic resonance imaging–guided focal boost to intraprostatic lesions using external beam radiotherapy for localized prostate cancer: A systematic review and meta-analysis. European Urology Oncology.

5. Mishra SK, Dhadve AC, Mal A, Reddy BPK, Hole A, CM Krishna, Ray P, Srivastava R, De A (2022). Photothermal therapy (PTT) is an effective treatment measure against solid tumors which fails to respond conventional chemo/radiation therapies in clinic. Biomaterials Advances.

Book Chapter
Ketkar M, Dutt S. (2022). Epigenetic regulation towards acquired drug resistance in cancer. In: Kundu TK, Das C. (Eds) Metabolism and epigenetic regulation: Implications in cancer. Subcellular Biochemistry, vol 100. Springer, Cham.

Site of the Week

SwissSidechain is a structural and molecular mechanics database of hundreds of non-natural amino-acid sidechains that can be used to study in silico their insertion into natural peptides or proteins.

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Interesting Reads

Giles JR, Ngiow SF, Manne S, Baxter AE, Khan O, Wang P, Staupe R, Abdel-Hakeem MS, Huang H, Mathew D, Painter MM, Wu JE, Huang YJ, Goel RR, Yan PK, Karakousis GC, Xu X, Mitchell TC, Huang AC, Wherry EJ. Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics. Nat Immunol. 2022.

Legends of Science
M.R.Narasimha Malur Ramaswamy-Iyengar Narasimha Prasad

M.R.Narasimha Prasad, an Indian endocrinologist, received his Ph.D. from the University of Mysore in 1945. He contributed significantly to reproductive physiology, fertility regulation, comparative endocrinology, and the use of non-human primates in biomedical research. He was the research and training coordinator at AIIMS, New Delhi, NIRR, Mumbai, and IISc, Bangalore. He was awarded the Fullbright Fellowship, USA, in 1955; the Knapp Centre Fellowship, University of Wisconsin, USA, in 1958; the National Family Planning Award in 1974 and the Jagdish Chandra Bose award in 1976.

Ram Parikshan Roy Ram Parikshan Roy

Ram Parikshan Roy obtained his Ph.D. from the University of Cambridge, UK, in 1953. His significant contribution was in cytogenetics, plant breeding, tissue culture, and cytotaxonomy. He located specific chromosome regions carrying the male maturity and fertility genes. He was the Coordinator UGC center of Special Assistance in Cytogenetics. Dr. Roy was the recipient of the Birbal Sahni Gold Medal. He was elected fellow of the National Academy of Sciences, Allahabad; Indian Society of Genetics and the Plant Breeding Society, London.

Upcoming Events
Cellular Lineages & Development from Single Cells to Landscapes

1-4 November, 2022

At Alleppey, Kerala.

Cell Bio 2022

03-07 December, 2022

At Washington, DC.

American Society of Hematology (ASH) Annual Meeting and Exposition

10-13 December, 2022

At New Orleans, LA

Do You Know?

In 2005, the drugs cetuximab (Erbitux) and panitumumab (Vectibix) were approved to treat colon cancer that has spread to other parts of the body (metastatis disease).

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Cancer News
Cancer drugs are closing in on some of the deadliest mutations

25 October 2022, Nature

The protein KRAS, mutated in many cancers, was deemed ‘undruggable’. Now scientists are hoping to save lives with a batch of new compounds that target it...

A key regulator of cell growth deciphered

27 October 2022, EurekAlert

In the absence of nutrients, the mTOR protein is blocked by the SEACIT subcomplex and cell growth is thus prevented...

Targeted lung cancer drug shows promise in phase I/II clinical trial

28 October 2022, MedicalXpress

The results of the TRIDENT-1 trial suggest that repotrectinib could be effective for treating ROS1 positive NSCLC, both in patients who have received other targeted treatments and in those who have not...

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