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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 05th September 2022 Vol. No. 11; Issue No. 542

1. Gholap D, Dikshit R, Chaturvedi P, Chaturvedi A, Majrekar A, Mhatre S (2022). Exclusive use of different types of tobacco products, exposure to second hand tobacco smoke and risk of subtypes of head and neck cancer among Indian males. International Journal of Cancer.

2. Dongre HN, Mahadik S, Ahire C, Rane P, Sharma S, Lukmani F, Patil A, Chaukar D, Gupta S, Sawant SS (2022). Diagnostic and prognostic role of protein and ultrastructural alterations at cell-extracellular matrix junctions in neoplastic progression of human oral malignancy. Ultrastructural Pathology.

Site of the Week

RegulonDB is a database of the regulatory network of gene expression in Escherichia coli K-12.

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Interesting Reads

Scholler N, Perbost R, Locke FL, Jain MD, Turcan S, Danan C, Chang EC, Neelapu SS, Miklos DB, Jacobson CA, Lekakis LJ, Lin Y, Ghobadi A, Kim JJ, Chou J, Plaks V, Wang Z, Xue A, Mattie M, Rossi JM, Bot A, Galon J. Tumor immune contexture is a determinant of anti-CD19 CAR T cell efficacy in large B cell lymphoma. Nat Med. 2022.

Legends of Science
Niraj Nath Dasgupta Niraj Nath Dasgupta

Niraj Nath Das Gupta secured his Ph.D. degree from the University of London in 1938 and a DSc Degree from the University of Kalyani. He did significant work in tracer studies on the uptake of radio-iodine in thyroid diseases and on the life span of human leucocytes in leukemia. He was the first to start electron microscopic research on bacterial chromosomes and the morphology of the kala-azar parasite and Mycobacterium leprae. Dr. Das Gupta was the recipient of the Mahenralal Sirkar Research Gold Medal in 1950; the NN Dutt Memorial Medal of the Indian Medical Association in 1965, and the Prize of Chittaranjan Cancer Hospital in 1972.

Ennapadam Sundra Ayyar Narayanan Ennapadam Sundra Ayyar Narayanan

Ennapadam Sundra Ayyar Narayanan obtained his Ph.D. from the University of London, the UK, in 1945. His research contribution covered the sub-disciplines of pure and applied entomology, taxonomy, anatomy, parasitology, field control operations, and biological control of insect pests and noxious weeds. As Director Central Sericultural Research Institute, he initiated investigations into experimental genetics, which led to the evolution of several new races of silkworms with superior commercial characteristics. Dr. Narayanan was a Fellow Royal Entomological Society, London; Indian Academy of Sciences, Bangalore, and National Academy of Sciences, Allahabad.

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Do You Know?

In 1996, Immunologist James Allison showed that blocking a molecule on immune cells called CTLA-4 could cure cancer in mice.

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Cancer News
Drug combo therapy in mice blocks drug resistance, halts tumor growth

31 August 2022, EurekAlert

In this study, researchers showed that small cell lung cancer cells resist cyclophosphamide by activating a specific repair process, and demonstrated that throwing a wrench into the repair process makes the drug much more effective, at least in mice...

Almost half of cancer deaths are preventable

31 August 2022, Nature

Almost half of cancer deaths are preventable. Nature, 31/08/2022 Nearly 50% of cancer deaths worldwide are caused by preventable risk factors, such as smoking and drinking alcohol, according to the largest study of the link between cancer burden and risk factors...

New method eradicates deadly brain tumors by 'starving' them of energy source

01 September 2022, MedicalXpress

The researchers achieved the outcome using a method they developed based on their discovery of two critical mechanisms in the brain that support tumor growth and survival: one protects cancer cells from the immune system, while the other supplies the energy required for rapid tumor growth...

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