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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 08 May 2023 Vol. No. 12; Issue No. 577

1. Mahadik P, Patwardhan S (2023). ECM stiffness-regulated exosomal thrombospondin-1 promotes tunneling nanotubes-based cellular networking in breast cancer cells. Archives of Biochemistry and Biophysics.

2. Nehra P, Singh Chauhan A, Malhotra P, Kumar L, Singh A, Gupta N, Mehra N, Mathew A, Kataki AC, Gupta S, Prinja S (2023). Cost-effectiveness analysis of different combination therapies for the treatment of chronic lymphocytic leukaemia in India. The Lancet Regional Health - Southeast Asia. 13: 100201.

3. Dey P, Gadewal N, De A (2023). Pathogenic HER3 dimerization domain mutations create a structural bias towards un-conventional EGFR-HER3 signalling axis in breast cancer. International Journal of Biological Macromolecules.

4. Murthy V, Maitre P, Singh M, Pal M, Arora A, Pujari L, Kapoor A, Pandey H, Sharma R, Gudipudi D, Joshi A, Prabhash K, Noronha V, Menon S, Mehta P, Bakshi G, Prakash G (2023). Study protocol of the Bladder Adjuvant RadioTherapy (BART) trial: A randomised phase III trial of adjuvant radiotherapy following cystectomy in bladder Cancer. Clinical Oncology.

Site of the Week

MitoProteome is an object-relational mitochondrial gene/protein sequence database and annotation system.

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Interesting Reads

Barisas DAG, Kabir AU, Wu J, Krchma K, Kim M, Subramanian M, Zinselmeyer BH, Stewart CL, Choi K (2023). Tumor-derived interleukin-1α and leukemia inhibitory factor promote extramedullary hematopoiesis. PLoS Biology. 21(5):e3001746.

Legends of Science
Balwant Rai Puri Balwant Rai Puri

Balwant Rai Puri obtained PhD from the University of Panjab in 1940. His interest areas were physical chemistry and surface chemistry. He contributed significantly to the research on the properties of capillary condensates, surface chemistry of carbons, catalytic reactions of industrial and environmental interest and physicochemical behaviour of proteins. He served as a member of the American Carbon Society. Dr Puri was a Fellow of the Royal Institute of Chemistry, London and Indian Chemical Society, and Founder President of the Indian Carbon Society.

Putcha Venkateswarlu Putcha Venkateswarlu

Putcha Venkateswarlu obtained his DSc from Banaras Hindu University in 1947. He extensively researched EPR, NMR, microwave spectra, laser-excited fluorescence, energy transfer and energy upconversion in rare earth ion doped crystals, nonlinear optics and optical phase conjugation. He discovered the first triatomic free radical CF2. It was an essential contribution as it ushered in the spectroscopy of free radicals. He initiated research in microwave and resonance spectroscopies (NMR & ESR). He was elected member of the Indian Academy of Sciences and the Indian National Science Academy. He was awarded C V Raman centenary medal in 1988.

Upcoming Events
Cell Symposia: Infection Biology in the Age of the Microbiome

07-09 June, 2023

At Paris, France.

Gene Therapy Development & Manufacturing 2023

13-14 June, 2023

At London, UK.

EMBO Workshop: Meiosis

18-23 June, 2023

At Pamhagen, Austria

Do You Know?

In 1997, FDA approved Rituxan (rituximab), the first monoclonal antibody, to treat non-Hodgkin’s lymphoma.

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Cancer News
Scientists break record for detecting smallest known melanoma lesion

03 May 2023, ExtremeTech

Oregon Health & Science University assistant professor Dr. Alexander Witkowski spotted a melanoma lesion measuring just 0.65 millimeters across, helping his patient to receive treatment before the cancer could spread...

Red flags indicate risk for early-onset colorectal cancer

04 May 2023, EurekAlert

Studying de-identified health insurance data on more than 5,000 patients with early onset colorectal cancer. The researchers found that in the period between three months and two years before diagnosis, abdominal pain, rectal bleeding, diarrhea and iron deficiency anemia each indicate an increased risk in those under age 50...

Reviving exhausted T cells to tackle immunotherapy-resistant cancers

04 May 2023, MedicalXpress

Researchers used an antibody to block the activity of PGSL-1 in mice with immunotherapy-resistant melanoma. They found that targeting PSGL-1 slowed the process of T cell exhaustion and helped exhausted T cells switch back into functioning T cells...

2023 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)