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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 2nd December 2024 Vol. No. 13 ; Issue No.658
Publications

1. Shinghal A, Pradhan S, Chopra S, Kapoor AR, Gupta A, Mittal P, Saini V, Jain J, Sanju S, Kapoor A, Giridhar P, Pujari L, Chowdhury Z, Gupta S (2024). Study protocol of Elective Para-aortic and pelvic versus Pelvic only Irradiation in pelvic node positive Cervical cancer: a multicentric open labelled phase III randomised controlled trial (EPIC Study). BMJ Open.14(11): .e08822

2. Noronha V, Menon N, Patil VM, Shah M, Joshi A, Shah S, Nawale K, Surve R, Bafna G, Jogdhankar S, Shelar P, Shetake A, Singh A, Salian S, Jadhav P, Shah H, Mer N, Vohra A, Majumdar S, Banavali S, Badwe R, Prabhash K (2024). Pregabalin for chronic cough due to lung cancer: randomized, double-blind, placebo-controlled trial. British Journal of Cancer.

3. Gadewal N, Patidar D, Natu A, Gupta S, Bastikar V (2024). In silico screening of phytochemicals against chromatin modifier, SETD7 for remodeling of the immunosuppressive tumor microenvironment in renal cancer. Molecular Diversity.

4. Piñeros M, Vignat J, Colombet M, Laversanne M, Ferreccio C, Heise K, Mhatre S, Koshiol J, Bray F (2024). Global variations in gallbladder cancer incidence: What do recorded data and national estimates tell us? International Journal of Cancer.

Site of the Week

The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models.

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Interesting Reads

Ren YF, Ma Q, Zeng X, Huang CX, Ren JL, Li F, Tong JJ, He JW, Zhong Y, Tan SY, Jiang H, Zhang LF, Lai HZ, Xiao P, Zhuang X, Wu P, You LT, Shi W, Fu X, Zheng C, You FM (2024). Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma. Molecular Cancer. 23(1):263.

Video of the Week
Chemotherapy-induced Cachexia and Model-informed Dosing to Preserve Lean Mass in Cancer Treatment
Upcoming Events
20th National Research Scholars Meet

11th - 12th December, 2024

At ACTREC, Tata Memorial Centre, Kharghar.

13th Annual Hands-on Workshop "In-vivo Preclinical Imaging & Drug Discovery

December 16-18, 2024

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai

An International Conference on Cellular Symphony - Decoding Protein Homeostasis in Human Health

February 3-5, 2025

At SRM Institute of Science & Technology, Kattankulathur

Do You Know?

In 1958, scientist developed 5-fluorouracil (5-FU), a chemotherapy drug used to treat many cancers. It is a first-line treatment for colon cancer.

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Cancer News
Glioblastoma treatment shows promise in mouse study

MedicalXpress, 28/11/2024

To investigate gliocidin's mechanism of action, researchers performed a genome-wide CRISPR–Cas9 knockout screen to identify genes that influence gliocidin's effectiveness against glioblastoma cells...

Study reveals how cancer cells evade chemotherapy in low-glucose environments.

News-Medical, 26/11/2024

For the study, researchers performed a scan of 3,000 cancer cell genes known to be involved in cell metabolism to determine, by deletion, which were necessary for cancer cell survival after chemotherapy. Most of the genes they found that were essential to cell...

Bone marrow progenitor-like cells against leukemia cure.

Nature Cancer, 25/11/2024

Relapse in T cell acute lymphoblastic leukemia (T-ALL) constitutes a challenge. A subclonal population of bone marrow progenitor-like cells present in all T-ALL genetic or immunophenotypic subtypes is now shown to confer chemoresistance and poor prognosis, and to be targetable with anti-apoptotic agents...

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