Advanced Centre for Treatment Research & Education in Cancer

Science Sparks @ ACTREC
27^th October 2025	Vol. No. 14 ; Issue No.706

Publications

1. Birwatkar S, Ghosh T, Selukar R, Lopes R, Khare NK, Raghuram GV, Shabrish S, Mittra I (2025). DsDNA breaks inflicted by cell-free chromatin particles selectively target telomeres. Scientific Reports. 15(1):36470.

2. Gupta S, Nair N, Hawaldar RW, Joshi S, Gulia S, Shet T, Sarin R, Parmar V, Desai S, Ghosh J, Wadasadawala T, Vanmali V, Panhale T, Parab P, Patil A, Chitkara G, Rath S, Bajpai J, Pathak R, Popat P, Thakur M, Badwe RA (2025). Addition of Carboplatin to Sequential Taxane-Anthracycline Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer: A Phase III Randomized Controlled Trial. Journal of Clinical Oncology.

3. Chakrabarty N, Bhalla AS, Jana M, Mahajan A (2025). Imaging spectrum of mesenchymal tumors of lungs and pleura. Journal of Thoracic Imaging. 40(6):e0839.

4. Srinivasan S, Aggarwal M, Patkar N, Gurjar P, Dhamne C, Roy Moulik N, Chichra A, Chatterjee G, Rajpal S, Tembhare P, Shetty D, Subramanian P.G, Narula G, Banavali S (2025). Prevalence and Prognostic Impact of NPM1 mutation in Childhood Acute Myeloid Leukemia: Experience from a Single Tertiary Cancer Centre in India. Clinical Lymphoma Myeloma and Leukemia.

Book
1. Prakash D, Kotian RP (2025): Fundamentals of X-ray Imaging: Basic Principles, Quality Control, Clinical Applications and Safety. Springer, Singapore (ISBN: 978-981-96-7327-8)

Site of the Week

RNAcentral is a public resource that offers integrated access to a comprehensive and up-to-date set of non-coding RNA sequences provided by a collaborating group of Expert Databases.

Interesting Reads

1. Researchers Spotlight: Priyanka Bagdiya-Decoding Allostery in 14-3-3: Insights on ATP’s Dual Regulatory Role. Biopatrika, 10/10/2025

2. Researchers Spotlight: Dr. Nazia Chaudhary-Dibita Mandal- Targeting the Sneaky GPX4–FSP1 Redox Switch to Defeat Drug-resistance in TNBC. Biopatrika, 07/10/2025

Video of the Week

Cancer Research with MRI: Deciphering the Alphabet Soup

Upcoming Events

Update in Prostate Cancer Focus on Theranostics

November 1-2, 2025

At ACTREC, Tata Memorial Centre, Kharghar

All About Spotting an Invention and Technology Commercialization

November 4, 2025

At ACTREC, Seminar Room, RRU 7th floor, Tata Memorial Centre, Kharghar

14th In Vivo Preclinical Imaging and Drug Discovery Hands-on Workshop

November 12-14 2025

At ACTREC, Tata Memorial Centre, Kharghar

Do You Know?

In 1978, Researchers developed and carry out the first trial of tamoxifen to prevent recurrence in breast cancer survivors.

Cancer News

Pancreatic cancer relies on opposing signalling pathways to drive its cellular diversity.

Nature, 22/10/2025

The researchers report that if mice are genetically engineered to prevent the expression of either the gene Spp1, which encodes SPP1, or the gene Itgb3, which encodes the SPP1 receptor called integrin β3 (ITGB3, also known as CD61), this prevents metastasis by blocking the formation of mesenchymal cells...

Researchers engineer a tool to dismantle cancer's RNA-built growth hubs.

News-Medical, 21/10/2025

The new study shows how RNA-normally just a messenger-gets hijacked to build liquid-like "droplet hubs" in the nucleus. These hubs act as command centers, switching on growth-promoting genes...

Scientists find immune drug that could halt skin cancer’s deadly spread.

Sciencedaily, 20/10/2025

Researchers found that pembrolizumab, an immune-activating cancer drug, lowered the risk of distant metastases in patients with Merkel cell carcinoma after surgery. Though recurrence rates overall weren’t significantly changed, the results hint at a meaningful benefit in preventing cancer spread...

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