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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 8th January 2024 Vol. No. 13 ; Issue No.612
Publications

1. Natu A, Verma T, Khade B, Thorat R, Gera P, Dhara S, Gupta S (2024). Histone acetylation: A key determinant of acquired cisplatin resistance in cancer. Clinical Epigenetics. 16:8.

2. Dandia HY, Pillai MM, Sharma D, Suvarna M, Dalal N, Madhok A, Ingle A, Chiplunkar SV, Galande S, Tayalia P (2024). Acellular scaffold-based approach for in situ genetic engineering of host T-cells in solid tumor immunotherapy. Military Medical Research.

3. Moharir S, Akotkar L, Aswar U, Kumar D, Gawade B, Pal K, Rane R (2024). Improved pharmacokinetic and pharmacodynamic profile of deuterium-reinforced tricyclic antidepressants doxepin, dosulepin, and clomipramine in animal models. European Journal of Drug Metabolism and Pharmacokinetics.

4. Kumar S, Castelino R, Rao A, Gattani S, Kumar A, Pillai A, Sehgal A, Rane P, Ramaswamy A, Dhekale R, Krishnamurthy J, Banavali S, Badwe R, Prabhash K, Noronha V, Gota V (2024). Performance of potentially inappropriate medications assessment tools in older Indian patients with cancer. Cancer Medicine.

5. Shinde U, De A, Godse R, Rathod M, Thorat R, Sharma N, Ansari M, Singh K (2024). Efficacy evaluation of carboplatin -etoposide Co-loaded PLGA microparticles for subconjunctival chemotherapy in retinoblastoma. Journal of Drug Delivery Science and Technology.

Theses
1. Dievya Dilip Gohil. 2023. Evaluation of phytochemicals with immunomodulatory activity for graft-versus-host disease prophylaxis. (LIFE09201604014) (Guide: Dr. Vikram Gota).

2. Suchita Dubey. 2023. Structural and functional basis to evaluate PML-RARA response to arsenic trioxide. (LIFE09201504008) (Guide: Dr. Ashok Varma).

Site of the Week

RandSeq is a tool which generates a random protein sequence.

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Interesting Reads

Penter L, Borji M, Nagler A, Lyu H, Lu WS, Cieri N, Maurer K, Oliveira G, Al'Khafaji AM, Garimella KV, Li S, Neuberg DS, Ritz J, Soiffer RJ, Garcia JS, Livak KJ, Wu CJ. Integrative genotyping of cancer and immune phenotypes by long-read sequencing. Nat Commun. 15(1): 32, 2024.

Video of the Week
The Elusive Role of Stellate Cells in Liver Cancer
Upcoming Events
46th All India Cell Biology Conference

January 10-12, 2024

At ACTREC, Tata Memorial Centre, Navi Mumbai

2024 ACS Cancer Conference

February 22-24, 2024

At Austin, TX

ESMO Targeted Anticancer Therapies Congress 2024

February 26-28, 2024

At Paris, France

Do You Know?

In 1993, Results from an NCI-supported clinical trial show that annual screening with guaiac fecal occult blood testing (FOBT) can reduce colorectal cancer mortality by about 33%.

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Cancer News
Game changer in cancer care: Tata hospital to unveil world’s largest nuclear therapeutic facility.

The Indian Express, 04/01/2024

The Advanced Centre for Treatment, Research, and Education in Cancer (ACTREC) at Kharghar is set to launch the world’s largest therapeutic nuclear facility within the next 2-3 months. Featuring 41 ‘hot beds’, this facility is poised to be a game-changer in treating severe cancers such as thyroid...

Breakthrough AI tool iStar revolutionises cancer diagnosis and treatment

The Week, 03/01/2024

The iStar tool allows doctors to see cancer cells that may have been difficult to identify with the naked eye By automatically detecting critical anti-tumor immune formations called "tertiary lymphoid structures," iStar can provide valuable information about a patient's likely survival and response to immunotherapy...

Scientists show reprogrammed fat cells support tumor growth.

MedicalXpress, 03/01/20224

The researchers treated immature adipocytes with a culture medium in which breast cancer cells with or without p53 mutations had previously grown. This treatment triggered profound changes in metabolism and gene activity in the adipocytes and increased the production of pro-inflammatory messengers...

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