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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 4th December 2023 Vol. No. 12 ; Issue No. 607

1. Srinivasan S, Dhamne C, Patkar N, Chatterjee G, Moulik NR, Chichra A, Pallath A, Tembhare P, Shetty D, Subramanian PG, Narula G, Banavali S (2023). KIT exon 17 mutations are predictive of inferior outcome in pediatric acute myeloid leukemia with RUNX1::RUNX1T1. Pediatric Blood Cancer.

2. Wadasadawala T, Datta D, Puchali N, Rane P, Sen S, Mohanty S, Gupta S, Sarin R, Parmar V (2023). Prospective Study of Incidence and Impact of Comorbidities on Breast Cancer Survival from India. Asian Pacific Journal of Cancer Prevention. 24(11):3805-3814.

3. Trivedi V, Noronha V, Sreekanthreddy P, Desai S, Poojary D, Varghese L, Gowda P, Butle A, Mishra R, Bal M, Mittal N, Rane S, Kane S, Basu S, Patil V, Menon N, Singh AK, Chaturvedi P, Chandrani P, Choughule A, Veldore V, Prabhash K, Dutt A. Association of Cutibacterium acnes with human thyroid cancer. Frontiers in Endocrinology . 14: 1152514.

4. Joshi P, Bhattacharya K, Menon MB, Ghosh Laskar S, Joshi A, Patil V, Chaturvedi P (2023). Malignant minor salivary gland neoplasms of larynx: Our experience. Polish Journal of Otolaryngology. 77(5):1-7

5. Mishra N, Dubey S, Kumari A, Khan MA, Kuligina ES, Preobrazhenskaya EV, Romanko AA, Yadav LR, Sarin R, Imyanitov EN, Varma AK (2023). Structural implications of amyloidogenic rare variants Ser282Leu and Gln356Arg identified in h-BRCA1. Proteins: Structure, Function, and Bioinformatics.

6. Gaur T, Ali A, Sharma D, Gupta SK, Gota V, Bagal B, Platzbeckar U, Mishra R, Dutt A, Khattry N, Mills K, Hassan Md., Sandur S, Hasan SK. Mitocurcumin utilizes oxidative stress to upregulate JNK/p38 signaling and overcomes Cytarabine resistance in acute myeloid leukemia. Cellular Signalling.

Site of the Week

TissGDB is the tissue-specific gene annotation database in cancer, aiming to provide a resource or reference for cancer and the related disease studies in the context of tissue specificity.

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Interesting Reads

Dondi A, Lischetti U, Jacob F, Singer F, Borgsmüller N, Coelho R; Tumor Profiler Consortium; Heinzelmann-Schwarz V, Beisel C, Beerenwinkel N (2023). Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer. Nature Communications. 27;14(1): 7780.

Video of the Week
Stratification of HCC Towards Precision Medicine
Upcoming Events
19th National Research Scholars Meet - NRSM

December 7 - 8, 2023

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai.

5th Annual Conference of Immuno-Oncology Society of India: I-OSICON 2024

January 12-14, 2024

At National Centre for Cell Science (NCCS), Pune

Single-Cell Biology: Tissue Genomics, Technologies and Disease

January 21 - 24, 2024

At Fairmont Hotel Vancouver, British Columbia, Canada

Do You Know?

In, 1903 S.W. Goldberg and Efim London first used radiation therapy to cure cancer. They made use of radium to treat two patients with basal cell carcinoma of the skin.

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Cancer News
Groundbreaking trial results expand treatment options for some people with bladder cancer.

National Cancer Institute, 30/11/2023

For the first time in decades, people with advanced bladder cancer have more effective treatment options, according to results of two large clinical trials. One treatment the combination of enfortumab vedotin (Padcev) and the immunotherapy drug pembrolizumab (Keytruda)proved to be particularly powerful…

Scientists find gene therapy reduces liver cancer in animal model.

MedicalXpress, 30/11/2023

Researchers have shown that inhibiting a specific protein using gene therapy can shrink hepatocellular carcinoma (HCC) in mice. Silencing the galectin 1 (Gal1) protein, which is often over-expressed in HCC, also improved the anti-cancer immune response and increased the number of killer T cells inside tumors…

Enhanced treatment of liver carcinoma with a drug-eluting hydrogel.

ScienceDaily, 29/11/2023

This drug-eluting hydrogel can provide sustained, pH-dependent drug co-delivery and has capabilities for promoting anti-tumor immune responses. This reduces tumor cell proliferation and growth and offers a more efficient means of enabling tumor cell death...

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