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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image 9 October 2023 Vol. No. 12; Issue No. 599

1. Chakraborty S, Baruah R, Mishra N, Varma AK (2023). In-silico and structure-based assessment to evaluate pathogenicity of missense mutations associated with non-small cell lung cancer identified in the Eph-ephrin class of proteins. Genomics and Informatics.21(3):e30.

2. Pandya RK, Jijo A, Cheredath A, Uppangala S, Salian SR, Lakshmi VR, Kumar P, Kalthur G, Gupta S, Adiga SK (2023). Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo quality. Andrology.

1. Pranay Dey. 2023. Imaging molecular interaction dynamics in drug resistance breast cancer. (LIFE09201704001) (Guide: Dr. Abhijit De)

2. Neelima. 2023. Characterization of long non-coding RNAs in human breast cancer. (LIFE09201604008) (Guide: Dr. Amit Dutt)

3. Bhasker D. 2023. Characterizing genome-wide aberrations that underlie oral cancer. (LIFE09201604004) (Guide: Dr. Amit Dutt)

Site of the Week

The DICE (Database of Immune Cell Expression, Expression quantitative trait loci (eQTLs) and Epigenomics) aims to understand the role of common genetic variations in human disease.

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Interesting Reads

Bahlis NJ, Costello CL, Raje NS, Levy MY, Dholaria B, Solh M, Tomasson MH, Damore MA, Jiang S, Basu C, Skoura A, Chan EM, Trudel S, Jakubowiak A, Gasparetto C, Chu MP, Dalovisio A, Sebag M, Lesokhin AM (2023). Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial. Nature Medicine.

Video of the Week
Announcement of the 2023 Nobel Prize in Chemistry
Upcoming Events
15th European Multidisciplinary Congress on Urological Cancers

02-05 November, 2023

At Marseille, France.

12th Annual New Therapeutics in Oncology: The Road to Personalized Medicine

10-11 November, 2023

At Los Angeles, CA.

Cellular Bases for Patient Response to Cancer Therapies

14-16 November, 2023

At Lyon, France.

Do You Know?

In 2012, Smart-seq, a method to generate high-coverage transcriptomes from single cells, was used to analyse the full-length messenger-RNA transcriptomes of circulating tumour cells from a patient with melanoma.

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Cancer News
Blood test for pan-cancer biomarker could revolutionize early cancer detection

05 October 2023, News-Medical

The new study leverages a single-molecule-based detection technology known as SIMOA.The test is designed to detect the open reading frame 1 protein (ORF1p), a transposable element protein that's known to occur in many cancers but not in corresponding normal tissue, and that can indicate high risk of cancer lethality...

New cancer drug targets uncovered using base editing and chemical proteomics

05 October 2023, EurekAlert

Combining precise genome engineering and protein activity profiling to methodically study thousands of cancer genes, Scripps Research scientists were able to pinpoint promising cancer drug targets...

Researchers develop new open-source method to improve decoding of single-cell data

05 October 2023, MedicalXpress

Researchers at Memorial Sloan Kettering Cancer Center (MSK) have developed a new open-source computational method, dubbed Spectra, which improves the analysis of single-cell transcriptomic data...

2019 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)