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Research Projects

Deciphering the tumor-associated functions of Pregnancy Zone Protein in Breast Cancer


Pregnancy Zone Protein (PZP), a proteinase inhibitor, has been implicated in etiology of various cancers. Through this study, we aim to identify and characterize novel interacting partners of PZP along with exploration of the TGFβ/SMAD pathway, TGFβ being a known interacting partner of PZP. Additionally, we aim to understand the role of PZP in cancer progression and metastasis using orthotopic xenograft murine models.

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