Enrichment, Isolation and Culture of Circulating Tumour Cells obtained from patients with metastatic or locally advanced breast cancer.

Oral cancer is one of the prevalent cancers in India associated with use of tobacco. Despite the improvement in medical technology and therapeutic approaches, the 5-year survival rate has not improved over the last 4–5 decades. Oral carcinogenesis is complex process involving series of histopathological changes. Carcinogen–induced hamster buccal pouch is well established model for oral carcinogenesis. It shows many changes analogous with human counterparts. Chemoprevention is emerging as an important modality for cancer prevention.

The identification and validation of predictive/prognostic biomarkers is one of the greatest challenges of cancer research. The lack of reliable biomarkers reduces the efficacy of anti-cancer drugs, ranging from cytotoxic chemotherapy to EGFR targeted therapy. Head and neck squamous cell carcinoma (HNSCC) is the sixth-most common malignancy worldwide with several distinct sub sites. Despite the new treatment strategies, survival of HNSCC patients has not improved significantly in the past three decades.