Our lab has been working on IGF-1R signalling to understand its role in chemo-resistance. Previous studies from our lab have shown oscillatory expression of IGF-1R across sensitive, early and late chemo-resistant ovarian cancer cells. IGF-1R is also known to promote several processes of metastasis like migration, invasion, angiogenesis etc. Therefore, I am trying to understand the role of IGF-1R in ovarian cancer metastasis using in vitro cell models and in vivo molecular imaging.
Junior Research Fellow