Principal Investigator
The research programme of the Cancer Genetics Unit has evolved over a decade from a clinical genetics programme to the present comprehensive programme including molecular genetics initiated after establishing the SARIN Lab in 2007 and now moving to population genetics. Several thousand subjects from ~1000 families with various hereditary cancer syndromes have been registered and a Bank of their Genomic DNA and EBV transformed lymphoblastoid cell line established. In addition there is a cohort of cases and controls with Multiple Primary Neoplasm (MPNs) and sporadic breast, thyroid or early age cancers with their genomic DNA banked.Biobanking of various tumour tissues with full clinical annotation has also been initiated. Utilizing these resources and collaborators, research has been initiated to examine 3 major aspects of cancer genetics:
The mutation spectra in ethnic Indian families with diverse hereditary cancer syndromes has been identified and… more
Breast Cancer – BRCAGEL Case Control Study : evaluating 25 SNPs and various reproductive, lifestyle, dietary, ch… more
Established a major programme under International Cancer Genome Consortium – India projectwhere high quality ann… more
This international collaborative project aims to establish a comprehensive catalogue of Genomic & other abno… more
It is now the Apex National Referral Centre for comprehensive clinical and laboratory genetic services and genet… more
Collaborative study with Prof Hebert, nutritional epidemiologist-(Univ. South Carolina) & leading Indian can… more
Res Asst BRCA GEL
Res Asst BRCA GEL
Graduate Student
Graduate Student
Graduate Student
Graduate Student
Co-Investigators
Co-Investigators
Scientific Assistant
Scientific Assistant
Co-Investigators
Co-Investigators
Scientific Assistant
Scientific Assistant
Scientific Assistant
Scientific Assistant
SRF ICMR
SRF ICMR
Mishra N, Dubey S, Kumari A, Khan MA, Kuligina ES, Preobrazhenskaya EV, Romanko AA, Yadav LR, Sarin R, Imyanitov EN, Varma AK (2024).
Gardi NL, Chaubal R, Parab P, Pachakar S, Kulkarni SS, Shet T, Joshi S, Kembhavi Y, Chandrani P, Quist J, Kowtal P, Grigoriadis A, Sarin R, Govindrajan R, Gupta S (2024).
Wadasadawala T, Mohanty S, Sen S, Kanala T, Maiti S, Puchali N, Gupta S, Sarin R, Parmar V (2024).
Wadasadawala T, Joshi S, Rath S, Popat P, Sahay A, Gulia S, Bhargava P, Krishnamurthy R, Hoysal D, Shah J, Engineer M, Bajpai J, Kothari B, Pathak R, Jaiswal D, Desai S, Shet T, Patil A, Pai T, Haria P, Katdare A, Chauhan S, Siddique S, Vanmali V, Hawaldar R, Gupta S, Sarin R, Badwe R(2024).