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Clinician

Dr. Sudeep Gupta

Dr. Sudeep Gupta

Director

Overview

Dr. Sudeep Gupta is a Professor of Medical Oncology at Tata Memorial Hospital in Mumbai, India. Dr. Gupta obtained his MBBS degree from All India Institute of Medical Sciences (AIIMS) in New Delhi in 1992. He completed his Postgraduate (MD degree) in internal medicine in 1994.

Achievements / Awards / Honors:

  • A graduate student in the lab is a recipient of the prestigious Prime Minister Fellowship for doctoral studies, awarded by DST-SERB and CII for the course of his Graduate thesis degree.

Affiliations and collaborations:

International Collaborations: Arizona State University, U.S.A.

Kings College London, U.K.

George Washington University, U.S.A.

National Collaborations: Centre for Development of Advanced Computing (CDAC), Pune.

Indian Institute of Technology (IIT-B), Bombay

National Centre for Cellular Sciences, (NCCS) Pune

National Institute of Biomedical Genomics (NIBMG), Kalyani

RESEARCH

The primary focus of clinician scientist laboratory (CSL) is on understanding the biological role of hypoxia in cancer metastasis & cancer spread, clonal evolution of a tumour leading to therapy resistance, and developing novel blood based assays to monitor tumour burden and response to therapy. Our laboratory comprises of an interdisciplinary group of surgical oncologists, medical oncologists, pathologists, basic scientists, and data scientists collaborating on addressing questions formulated from clinical observations. Our laboratory uses a bedside - to bench - to bedside approach where-in observations from the clinics generate a hypothesis. We then test this hypothesis using pre-clinical assays. Big data generated from patient samples using OMICS technologies integrate with, and inform, these pre-clinical assays. We use a variety of model systems including in-vitro cell-based assays, in-vivo animal studies and 3D organoid cultures to address our research questions. The eventual goal of our laboratory is to translate our pre-clinical findings in the laboratory into relevant interventions addressing clinical problems. Our laboratory is the nodal laboratory for the multi-omics endocrine hormone resistance study in breast cancer initiative under the aegis of the Virtual National Cancer Institute (VNCI) endeavor by the Department of Biotechnology, Govt. of India.

Ongoing Research Projects

  • project1

    Our laboratory is engaged in multiple research studies with translational relevanc…

    The proluton studymore

  • project1

    IRB study 168, the hypoxia study

    funded by the Tata Memorial Centre explores the role of peri-operative… more

  • project1

    IRB study 151 (CTRI Identifier: CTRI/2016/11/007430), the Mapping study

    is funded by the Department of… more

  • project1

    IRB study 187, (CTRI Identifier : CTRI/2016/09/007308) the ctDNA study

    funded by the Tata Memorial Centre, aims to investigate the utility of… more

  • project1

    IRB study 239, (CTRI Identifier: CTRI/2017/11/010553) the Virtual National Cancer…

    is a flagship study funded by the Department of Biotechnology, Governm… more

  • project1

    IRB study 272, the AP-1 study

    aims to identify the role of AP-1 (Activator protein-1) subunit comple… more

Lab Members

PUBLICATIONS

Contact

Office Contact

Dr. Sudeep Gupta

KS/38, Clinician Scientist Lab, Advance Centre for Treatment Research & Education in Cancer, Tata Memorial Centre, (ACTREC), Plot No. 1 & 2, Sector 22, Kharghar, Navi Mumbai-410210. Maharashtra India.+91 (022) 2740 5000/ 6873 5000 sudeep.gupta@actrec.gov.in Lab Website

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