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Principal Investigator

Dr. Nazia Chaudhary

Dr. Nazia Chaudhary

DST Inspire Fellow

Honors and Recognitions

DST INSPIRE FACULTY FELLOWSHIP (2022)
Member of the Board of Studies (Zoology), Sophia college (2018-2021)
Best poster presentation at 14th Indo – Australian Biotechnology conference (2018)
JGEEBILS (2015)
K.C. MAHINDRA HONOUR'S AWARD (2013)
Sajjan Gupta Konark Memorial Award (2013)
Saifee Education Aid programme scholarship for standing FIRST in the T.Y.B. Sc Microbiology. (2013)
Ramidevi Murlidhar Jalan ROTARY MIDTOWN Best Student award. (2012-2013).
Vaishno Endowment -Shanti Malhotra award for the BEST ALL ROUND STUDENT. (2012-2013)
Mahindra Search for Talent Scholarship (2011-2012) and (2012-2013)
Madholal Sindhoo Memorial Scholarship. (2012)
Mrs. A. Verghese Prize for a constantly OUTSTANDING zoology student (2012).
Mrs. Margaret Rebello Sequeira prize. (2010-2011)

Research Interests

Therapy resistance.
Role of Lipid metabolism (De novo lipogenesis, insulin resistance and fatty acid oxidation) in tumor progression and drug resistance.
Ferroptosis in drug resistance, cellular metabolism, and tumor suppression.
Cysteine metabolism induced nutrient dependency.
Nutrient signaling and scavenging pathways.
Signet ring cell carcinoma.
PDX, PDO, and peritoneal metastasis model system development.

PUBLICATIONS

2025
Patient-derived Organoids and Xenografts Uncover Therapeutic Vulnerabilities in Colorectal Signet Ring Cell Carcinomas. Clinical Cancer Research.
Chaudhary N, La Ferlita A, Choudhary BS, Jog E, Kazi M, Yahya S, Dalwai A, Ostwal V, Kumar S, Redkar S, Khapare N, Kailaje V, B A, Gera P, Bal M, Verma N, Thorat R, Saklani A, Sehgal L, Dalal SN (2025)
Low-GPX4 drives a sustained drug-tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation. Redox Biology.
Chaudhary N, Mandal D, Choudhary B, Patra S, Jain D, Poonia P, Shaikh S, Tekalkar S, Malvankar S, Shivashankar A, Jog E, Pilankar L, Thorat R, Kailje V, Khanna S, Manna S, Khan B, Jadhav A, Sharma K, Ramu S, Sahoo S, Jolly MK, Dalal SN, Sinha S, Nair N, Ruppin E, Lamballe F, Maina F, Verma N
EGFR-to-Src family tyrosine kinase switching in proliferating-DTP TNBC cells creates a hyperphosphorylation-dependent vulnerability to EGFR TKI. Cancer Cell International. 25(1):55. PMID: 39972345.
Chaudhary N, Choudhary BS, Shivashankar A, Manna S, Ved K, Shaikh S, Khanna S, Baar J, Dani J, Sahoo S, Soundharya R, Jolly MK, Verma N
Inhibiting de novo lipogenesis identifies a therapeutic vulnerability in therapy-resistant colorectal cancer. Redox Biology.79:103458.
Jog E, Jainarayanan AK, Ferlita A, Chakraborty A, Dalwai A, Yahya S, Shivashankar A, Choudhary B, Chandramouli A, Kazi M, Jain D, Khapre N, Akshaya B, Khan B, Gera P, Patil P, Thorat R, Verma N, Sehgal L, Saklani A, Kamat S, Dalal SN, Choudhary N (2025).

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Contact

Office Contact

Dr. Nazia Chaudhary

KS 231, Advance Centre for Treatment Research & Education in Cancer, Tata Memorial Centre, (ACTREC), Plot No. 1 & 2, Sector 22, Kharghar, Navi Mumbai-410210. Maharashtra India. nchaudhary[at]actrec[dot]gov[dot]in

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