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Transplant Immunology & Immunogenetics

Transplant Immunology & Immunogenetics

Staff

Officer In-charge : Dr. Meenakshi Singh

Overview

The Transplant Immunology and Immunogenetics Laboratory (TII / HLA) at ACTREC – TMC is a NABL accredited laboratory with state-of-the-art equipment.

The laboratory offers specialized diagnostic testing services including HLA Typing by Low and High Resolution for haematological malignancies (Acute Myeloid Leukemia (AML), B/T cell -Acute Lymphoblastic Leukemias (B-ALL/T-ALL), Chronic Myeloid Leukemia (CML), Chronic lymphocytic Leukemia (CLL), Myelodysplastic syndromes/Myeloproliferative neoplasms (MDS/MPN), Chronic Myelomonocytic Leukemia (CMML), Multiple Myeloma (MM) and Lymphomas). Additionally, KIR Genotyping and HLA Antibody Screening assays are also offered in order to select a suitable donor for Haploidentical Hematopoietic Stem cell Transplants. The lab also facilitates in identifying HLA matched and epitope matched platelet donors for patients with platelet refractoriness. Diagnostic HLA testing services for disease associations, drug hypersensitivity, and recurrent pregnancy loss are also under the test scope of the laboratory. The laboratory accepts requests for all the above diagnostic tests from all the TMC centres as well as other referral laboratories within the country.

The Laboratory ensures high accuracy of reporting by participating in External Quality Assessment program(EQAS) with All India Institute of Medical Sciences(AIIMS) and Inter-lab comparison program with MGUMST, Jaipur.

The laboratory staff is a highly skilled team of Scientific Officers, Scientific Assistants, and Administrative staff.

Laboratory provides following tests
HLA Genotyping Assays
  • Low resolution HLA typing by Sequence specific primer (SSP) method
  • Low resolution HLA typing by Sequence specific oligonucleotide probe (SSO) method
  • High resolution sequence based HLA typing by Sangers Sequencing method (SBT)
  • High resolution sequence based HLA typing by Next Generation Sequencing (NGS) method
  • Killer Cell Immunoglobulin Receptor (KIR) genotyping by Sequence specific primer (SSP) method
HLA DRUG HYPERSENSITIVITY
  • HLA DRB1*15- Cyclosporine/Tacrolimus
  • HLA B*58:01- Allopurinol
  • HLA B*57:01- Abacavir
  • HLA B*13:01- Dapsone
  • HLA A*31:01- Carbamezapine
  • HLA B*15:02- Phenytoin
DISEASE ASSOCIATION
  • HLA B*27 Ankylosing Spondylitis
  • HLA B*51 Behcets Disease
  • HLA DRB*1 Rheumatoid Arthritis
FREQUENT SPONTANEOUS ABORTION
  • HLA G*
Alloimmunization testing
  • Single Antigen Bead based assay using Luminex technology for HLA Class I and Class II antigens
  • Single Antigen Bead based assay using Luminex technology for C3d complement binding antibody [C3d Single Allele Antibody Class I & II]
HLA Testing for Other Purposes

In addition to the services described above for transplant patients, HLA testing for the following conditions are also performed:

  • Platelet transfusion support: Patients with low platelet counts are at risk for serious bleeding complications and are often transfused with platelets from healthy donors. However, patients can sometimes produce antibodies to the HLA molecules expressed on platelets, which reduce the effectiveness of platelet transfusion. HLA typing and antibody detection help physicians choose a platelet donor that will result in increased platelet counts for patients in need.
Information for Outside Referrals

The lab accepts referral samples for HLA typing, KIR genotyping and HLA antibody screening from hospitals within the country. The requirements for sending the samples are as follows: HLA Typing and KIR Genotyping: Blood sample for HLA typing and KIR genotyping must be collected in EDTA or Sodium Citrate vacutainers 10 ml (2.5 ml x 4 tubes) peripheral blood. HLA Antibody screening blood sample must be collected in a single plain tube (5 ml peripheral blood).

Please ensure that the samples reach the TII Lab, ACTREC, within 72 hours of collection All collected samples should be sent along with the clinicians request on their respective hospital’s letterhead and the filled sample transportation form to HLA OPD, located at Room no. 307, Shanti Sadan Building, ACTREC, Kharghar between 2.30pm to 4.00pm, from Monday to Friday (Except public holidays).

Please find below the Sample transportation form to be sent with all transported samples. It is mandatory to fill the name of patient/donor, location of collection, phlebotomist name, sign with the collection date & time.

Protocol for sample transportation (UPDATED)_21.10.2024.pdf

Education and Courses

Our department is part of the Homi Bhabha National Institute and offers a range of comprehensive educational programs, including:

  • Fellowship Programs:One-year Advanced training in Transplant Immunology & Immunogenetics is designed to provide candidates with theoretical as well as hands on experience in the areas of transplant immunogenetics. The fellowship program is advertised on the website www.tmc.gov.in.

  • MScDissertation: The lab offers 3-6 months (short term) research projects to students in the final year of their post-graduation degree in LifeSciences/Biotechnology/Immunology

  • Observers:The lab conducts 15 days to 1-month Observership to medical post-graduates, scientists, science undergraduates, graduates and post-graduates from India and from other countries

    • The information regarding dissertation and observership can be sought from the Academic Cell for Clinical Services. Contact Tel: 022 6873 5000. (Ext. 5730). Email ID : tii.hla@actrec.gov.in

Research

The laboratory is involved in various research projects in collaboration with the Bone Marrow transplant unit, ACTREC. The research area is broadly focused on the different aspects of Transplant Immunology & Immunogenetics in relation to various hemato-lymphoid and solid organ transplants.

The lab also focuses on translational research using molecular, proteomics, etc. in developing Lab-to-Clinic oriented novel assays with implications in the diagnosis and prognosis of transplant patients resulting in better treatment outcomes and patient care. Pharmacogenomics and disease association in relation to HLA is also being explored.

Recently, the lab has forayed into the area of Immunotherapy, by successfully generating Virus specific T cells (R & D grade) which could be used to treat patients with common post-transplant infections such as AdV, CMV and EBV. Basic research focused on NK cell cytotoxicity with a probability of developing novel CAR-NK immunotherapy products is also being undertaken.

These projects have been funded by Terry Fox Cancer foundation, DBT-BIRAC and intramural grants. The laboratory has regular publications in national and international peer reviewed journals.

Participation in International Workshops
TII Lab in the past has been a part of the international consortium on Immunogenetics by participating in the 18th International HLA & Immunogenetics Workshop (IHIW), held in Netherlands from 11th -15th May 2022.

The lab participated in the following components of the workshop:

  1. Population genetics, anthropology and evolution
    For this component, the lab performed high resolution (NGS) HLA typing for 11 loci in 184 unrelated healthy donors from India. A total of 25 novel alleles were observed, which have been added to the IMGT database and have been published in the peer reviewed HLA journal (Impact Factor 9.2)
  2. High-resolution KIR in populations
    As part of this component, KIR high resolution typing (NGS) was conducted for the KIR inhibitory genes in 120 unrelated healthy donors from India. This is the first data from Indian population.
Publications (2019-2025)
  1. Andrea S. Pinto, Jyoti Rajak, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-A*01:01:01:111 allele in two individuals from Uttar Pradesh, India DOI: https://doi.org/10.1111/tan.15021

  2. Jyoti Rajak, Andrea S. Pinto, Selma Z. D'Silva, Meenakshi Singh Identification of the HLA-B*40:01:02:59 and -C*05:01:73 alleles in individuals from the northern regions of India DOI: https://doi.org/10.1111/tan.15030

  3. Selma Zenia D’Silva, Anand Bodade, Shalaka Kadam, Manisha Tambe, Sandeep Dhanda ·Bhausaheb Bagal, Manju Sengar, Hasmukh Jain, Lingaraj Nayak, Avinash Bonda, Sachin Punatar, Anant Gokarn, Navin Khattry, Meenakshi Singh, Frequency of HLA alleles and KIR Ligands in Acute Myeloid Leukemia in Indian Cohort DOI: 10.1007/s12288-022-01550-0

  4. Bansi S. Parsaniya, Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA allele, HLA-DRB1*14:245, in an individual from Northern India DOI : https://doi.org/10.1111/tan.14784

  5. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva,Meenakshi Singh Identification of the novel HLA-B*51:01:01:108 allele and confirmation of HLA-B*40:387 in two Indian individuals DOI : https://doi.org/10.1111/tan.14785

  6. Bansi S. Parsaniya, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the HLA-A allele, HLA-A*11:03:01:02, in two individuals in a Western Indian family DOI: https://doi.org/10.1111/tan.14787

  7. Selma Z. D'Silva, Manisha Tambe, Andrea S. Pinto, Meenakshi Singh The novel HLA-B*52:01:01:23 allele in an individual from Uttar Pradesh, North India DOI : https://doi.org/10.1111/tan.14812

  8. Jyoti Rajak, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DPA1*02:82 allele in a Punjabi individual DOI:https://doi.org/10.1111/tan.14805

  9. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DQB1*06:01:01:04 allele in an individual from Western India DOI : https://doi.org/10.1111/tan.14809

  10. Selma Z. D'Silva, Manisha Tambe, Andrea Pinto, Meenakshi Singh Identification of the novel HLA-DQB1*04:02:01:18 allele in a Maharashtrian individual from India DOI: https://doi.org/10.1111/tan.14789

  11. Manisha Tambe, Selma Z. D'silva, Andrea S. Pinto, Bansi Parsaniya, Meenakshi Singh Identification of the novel allele, HLA-A*02:11:01:06, in two North Indian individuals in a Kshatriya family DOI: https://doi.org/10.1111/tan.14814

  12. Selma Z. D'Silva, Manisha Tambe, Andrea S. Pinto, Meenakshi Singh Identification of the novel allele, HLA-C*06:02:38:02, in a Gujarati individual from India DOI: https://doi.org/10.1111/tan.14813

  13. Manisha Tambe, Selma Z. D'Silva, Bansi Parsaniya, Andrea S. Pinto, Meenakshi Singh Identification of HLA-C*03:599 novel allele variant in two South Indian individuals in a Brahmin family DOI: https://doi.org/10.1111/tan.14815

  14. Bansi S. Parsaniya, Andrea S. Pinto, Selma Z. D'Silva, Meenakshi Singh Characterization of the novel HLA allele, HLA-C*07:04:01:19, in an individual from Maharashtra, India DOI : https://doi.org/10.1111/tan.14825

  15. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva,Meenakshi Singh Identification of the novel HLA-C*12:02:47 allele in an individual from Maharashtra, India DOI : https://doi.org/10.1111/tan.14826

  16. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DQA1*01:01:01:10 allele in an individual from Orissa, India DOI : https://doi.org/10.1111/tan.14836

  17. Manisha Tambe, Selma Z. D'Silva, Jyoti Rajak, Andrea S. Pinto, Meenakshi Singh The novel HLA-B*40:02:01:39 allele in an individual from a Kshatriya family in North India DOI : https://doi.org/10.1111/tan.14849

  18. Manisha Tambe, Selma Z. D'Silva, Andrea S. Pinto, Meenakshi Singh Characterization of the novel HLA-B*58:01:01:19 allele by next-generation sequencing DOI: https://doi.org/10.1111/tan.14850

  19. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva,Meenakshi Singh Identification of the novel HLA-DPA1*01:03:01:64 allele in an individual from Uttar Pradesh, India DOI: https://doi.org/10.1111/tan.14857

  20. Manisha Tambe, Jyoti Rajak, Andrea S. Pinto, Selma Z. D'Silva,Meenakshi Singh Identification of the novel HLA allele, HLA-B*37:01:01:19, in an individual from northern India DOI: https://doi.org/10.1111/tan.14860

  21. Manisha Tambe, Selma Z. D'Silva, Andrea S. Pinto, Meenakshi Singh Identification of the novel HLA-C*07:02:01:184 allele in an Indian individual from a Kshatriya family DOI : https://doi.org/10.1111/tan.14865

  22. Tenzin Phuntsok, Jyoti Rajak, Selma Z. D'Silva, Manisha Tambe, Meenakshi Singh. Characterization of the novel HLA-B*51:01:01:83 allele in three individuals from North India. 06 October 2021,HLA DOI: https://doi.org/10.1111/tan.14446

  23. Jyoti Rajak, Selma Z. D'Silva, Manisha Tambe, Tenzin Phuntsok, Meenakshi Singh. Identification of a novel HLA-DPB1*02:01:61 allele in an Indian individual. 06 October 2021, HLA DOI: https://doi.org/10.1111/tan.14445

  24. Tenzin Phuntsok, Manisha Tambe, Selma Z. D'Silva, Jyoti Rajak, Meenakshi Singh. Characterization of novel HLA-B*13:02:01:18 allele in a North Indian individual. 06 October 2021, HLA DOI: https://doi.org/10.1111/tan.14443

  25. Tenzin Phuntsok, Selma Z. D'Silva, Manisha Tambe, Jyoti Rajak, Meenakshi Singh.Characterization of the novel HLA‐B*52:01:01:18 allele in a West Indian individual. 06 October 2021, HLA DOI: https://doi.org/10.1111/tan.14448

  26. Tenzin Phuntsok, Selma Z. D'Silva, Manisha Tambe, Meenakshi Singh. Identification of the novel HLA-B*35:03:01:22 allele in an individual of Nepalese origin. July 2021, HLA DOI: https://doi.org/10.1111/tan.14353

  27. Selma Z. D'Silva, Manisha Tambe, Jyoti Rajak, Tenzin Phuntsok, Meenakshi Singh. Identification of the novel HLA-C*14:02:01:22 allele in an Indian individual. July 2021, HLA DOI: https://doi.org/10.1111/tan.14352

  28. Selma Z. D'Silva, Tenzin Phuntsok Manisha Tambe, Jyoti Rajak, Meenakshi Singh. Identification of a novel HLA-A*24 allele, A*24:537, identified in three individuals in an Indian family. July 2021, HLA DOI: https://doi.org/10.1111/tan.14355

  29. Manisha Tambe, Tenzin Phuntsok, Selma Z. D'Silva, Jyoti Rajak, Meenakshi Singh. Characterization of a novel HLA‐C *04:01:01:102 allele in an individual from West Bengal. July 2021, HLA DOI: https://doi.org/10.1111/tan.14363

  30. Mohapatra S, Menon NG, Mohapatra G, Pisharody L, Pattnaik A, Menon NG, Bhukya Prudhvi Lal, Srivastava M, Singh M, Barman MK, Gin KY, Mukherji S. The novel SARS-CoV-2 pandemic: Possible environmental transmission, detection, persistence and fate during wastewater and water treatment. Sci Total Environ. 2020 Oct 6:142746. PMID: 33092831; PMCID: PMC7536135. DOI: https://doi.org/10.1016/j.scitotenv.2020.142746

  31. D’Silva SZ, Dhanda SK, Singh M. Killer immunoglobulin like receptor gene profiling in Western Indian population. Hum. Immunol. 2019; (19): 30206.

  32. D’Silva SZ, Punatar S, Gokarn A, Bonda A, Tambe M, Matthew L, Kannan S, Khattry N, Singh M. Implication of patient KIR ligands and donor KIR genotypes on transplant outcomes in T cell replete haploidentical transplant with post-transplant cyclophosphamide.

  33. D’Silva SZ, Dhanda SK, Rajadhyaksha SB., Khattry N, Singh M. Diversity of Killer Immunoglobulin like receptor genes, alleles, and their genotypes among the Western Indian population. Genetic Testing and Molecular Biomarkers.

  34. Sharma S, Sharma U, Chaudhary A, Naithani M, Naithani P, Prashar S, Sharma B, Nagar PK,Bhukya PL, Bhalerao U, Singh M. , Srivastava M, Barman MK, Attri S, Gairolla J. SARS-CoV-2:Insights from the Immunopathogenesis and Current Clinical Diagnosis and Therapeutic Strategies. J Immunological Sci. (2021); 5(2): 1-15

  35. D'Silva SZ, Tambe M, Singh M. The Novel MICA*010:01:15 Allele in an Individual from West Bengal, India. HLA. 2025 May;105(5):e70059.PMID: 40320791.

  36. Firfire A, Rajak J, Tambe M, D'Silva SZ, Singh M. HLA-A*02:11:01:08 and HLA-A*11:01:01:91 Identified in Two Unrelated Prospective Bone Marrow Donors in India. HLA. 2025 May;105(5):e15763.PMID: 40323281.

  37. Jindal N, Patel K, Garg M, Mirgh S, Chichra A, Nayak L, Gokarn A, Punatar S, Bagal B, Mathew LJ, D'Silva S, Singh M, Khattry N. High Risk of Graft Rejection in Patients with HLA Homozygosity Following Haploidentical Transplant Using Post-Transplant Cyclophosphamide. Blood Cell Ther. 2025 Feb 7;8(1):167-169.PMID: 40061176; PMCID: PMC11883474.

  38. Jyoti Rajak , Alfiya Firfire , Manisha Tambe , Selma Z D'Silva , Meenakshi Singh Identification of the novel HLA-C*01:02:01:74Q and -C*15:02:01:63 alleles in individuals from Madhya Pradesh Abstract Allele variants HLA-C*01:02:01:74Q and -C*15:02:01:63 differ from -C*01:02:01:01 and -15:02:01:01 by a single nucleotide, respectively.

  39. Jyoti Rajak, Alfiya Firfire, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the HLA-B*15:679 and HLA-C*15:02:01:61 alleles in individuals from eastern India Journal : HLAVolume103, Issue6, June 2024, e15563

  40. Selma Zenia D’Silva, Anand Bodade, Shalaka Kadam, Manisha Tambe, Sandeep Dhanda, Bhausaheb Bagal, Manju Sengar, Hasmukh Jain, Lingaraj Nayak, Avinash Bonda, Sachin Punatar, Anant Gokarn, Navin Khattry & Meenakshi Singh Frequency of HLA alleles and KIR Ligands in Acute Myeloid Leukemia in Indian Cohort

  41. SZ D'Silva, M Singh, AS Pinto, NK cell defects: implication in acute myeloid leukaemia. Frontiers of Immunology, Volume 14 - 2023.

  42. Jyoti Rajak, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh, Identification of the HLA-B*15:665 and HLA-C*12:02:02:23 alleles in individuals from the South Asia Journal : HLAVolume102, Issue5, November 2023, Pages 625-626

  43. Jyoti Rajak, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh, Identification of the novel HLA-C*06:02:01:94 and -C*15:02:01:58 alleles in individuals from Madhya Pradesh Journal : HLAVolume102, Issue5, November 2023, Pages 634-635

  44. Jyoti Rajak, Andrea S. Pinto, Selma Z. D'Silva, Meenakshi Singh, Identification of the HLA- B*40:01:02:59 and -C*05:01:73 alleles in individuals from the northern regions of India Journal : HLAVolume102, Issue1, July 2023, Pages 80-81

  45. Andrea S. Pinto, Jyoti Rajak, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh, Identification of the novel HLA-A*01:01:01:111 allele in two individuals from Uttar Pradesh, India Journal : HLAVolume102, Issue1, July 2023, Pages 65-66

  46. Jyoti Rajak, Bansi Parsaniya, Andrea S. Pinto, Selma Z. D'Silva, Meenakshi Singh, Detection of novel HLA-A*33:03:62, HLA-B*52:01:01:25 alleles and confirmation of HLA-A*02:01:209Journal : HLAVolume101, Issue3, March 2023, Pages 273-274

  47. Selma Z. D'Silva, Manisha Tambe, Andrea S. Pinto, Meenakshi Singh, Identification of the novel HLA-DQA1*01:01:01:11 and -DQA1*01:03:01:13 alleles in individuals from India Journal : HLAVolume101, Issue3, March 2023, Pages 296-297

  48. Manisha Tambe, Selma Z. D'Silva, Andrea S. Pinto, Meenakshi Singh, Identification of the novel HLA-C*07:02:01:184 allele in an Indian individual from a Kshatriya family Journal : HLAVolume101, Issue2, February 2023, Pages 182-183

  49. Manisha Tambe, Jyoti Rajak, Andrea S. Pinto, Selma Z. D'Silva, Meenakshi Singh, Identification of the novel HLA allele, HLA-B*37:01:01:19, in an individual from northern India Journal : HLAVolume101, Issue2, February 2023m Pages 163-164

  50. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DPA1*01:03:01:64 allele in an individual from Uttar Pradesh, India Journal : HLAVolume101, Issue2, February 2023, Pages 198-199

  51. Manisha Tambe, Selma Z. D'Silva, Andrea S. Pinto, Meenakshi Singh Characterization of the novel HLA-B*58:01:01:19 allele by next-generation sequencing Journal : HLAVolume101, Issue2, February 2023, Pages 173-174

  52. Manisha Tambe, Selma Z. D'Silva, Jyoti Rajak, Andrea S. Pinto, Meenakshi Singh The novel HLA-B*40:02:01:39 allele in an individual from a Kshatriya family in North India Journal : HLAVolume101, Issue2, February 2023, Pages 164-165

  53. Manisha Tambe, Selma Z. D'Silva, Andrea S. Pinto, Meenakshi Singh Identification of the novel HLA allele, HLA-A*11:01:01:86, in an individual from north India Journal : HLAVolume101, Issue2, February 2023, Pages 153-154

  54. Manisha Tambe, Selma Z. D'Silva, Jyoti Rajak, Andrea S. Pinto, Meenakshi Singh Identification of the novel HLA-A*24:02:01:136 allele in a Northern Indian individual from a Muslim family Journal : HLAVolume101, Issue2, February 2023, Pages 158-159

  55. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DQA1*01:01:01:10 allele in an individual from Orissa, India Journal : HLAVolume101, Issue2, February 2023, Pages 190-191

  56. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-C*12:02:47 allele in an individual from Maharashtra, India, Journal : HLAVolume101, Issue1, January 2023, Pages 74-75

  57. Bansi S. Parsaniya ,Andrea S. Pinto, Selma Z. D'Silva, Meenakshi Singh Characterization of the novel HLA allele, HLA-C*07:04:01:19, in an individual from Maharashtra, India, Journal : HLA, Volume101, Issue1, January 2023, Pages 71-72

  58. Manisha Tambe, Selma Z. D'Silva, Bansi Parsaniya, Andrea S. Pinto, Meenakshi Singh , Identification of HLA-C*03:599 novel allele variant in two South Indian individuals in a Brahmin family, Journal : HLA, Volume101, Issue1, January 2023, Pages 66-67

  59. Manisha Tambe, Selma Z. D'silva, Andrea S. Pinto, Bansi Parsaniya, Meenakshi Singh, Identification of the novel allele, HLA-A*02:11:01:06, in two North Indian individuals in a Kshatriya family, Journal : HLA, Volume101, Issue1, January 2023, Pages 43-44

  60. Selma Z. D'Silva, Manisha Tambe, Andrea S. Pinto, Meenakshi Singh, Identification of the novel allele, HLA-C*06:02:38:02, in a Gujarati individual from India, Journal : HLA, Volume101, Issue1, January 2023, Pages 69-70

  61. Selma Z. D'Silva, Manisha Tambe, Andrea S. Pinto, Meenakshi Singh The novel HLA-B*52:01:01:23 allele in an individual from Uttar Pradesh, North India, Journal : HLA, Volume101, Issue1, January 2023, Pages 56-57

  62. Andrea S. Pinto, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DQB1*06:01:01:04 allele in an individual from Western India, Journal : HLA, Volume101, Issue1, January 2023, Pages 90-91

  63. Jyoti Rajak, Manisha Tambe, Selma Z. D'Silva, Meenakshi Singh Identification of the novel HLA-DPA1*02:82 allele in a Punjabi individual, Journal : HLA, Volume101, Issue1, January 2023, Pages 94-95

  64. Sanchez-Mazas A.;Nunes J.M.;Di D.;Dominguez E.A.;Gerbault P.;Faye N.K.;Almawi W.;Andreani M.;Arrieta-Bolanos E.;Augusto D.G.;Buhler S.;de Groot N.G.;Díaz-Peña R.;D'Silva S.;Dubois V.;ElGhazali G.;Gorodezky C.;Grubić Z.;Hajeer A.;Hollenbach J.;Issler H.C.;Ivanova M.;Jawdat D.;Kanga U.;Kirijas M.;Lemieux W.;Loginova M.;Mahfoudh N.;Mehra N.;Mouron D.;Petřek M.;Petzl-Erler M.L.;Richard L.;Roelen D.L.;Sacchi N.;Sharma A.;Singh B.;Singh M.;Singh Y.;Tarassi K.;Vidan-Jeras B.;Villard J. The most frequent HLA alleles around the world: A fundamental synopsis

Contact Details
Laboratory Office Number: (+9122) 68735000 / Ext. No. 5828 /5820
Transplant Immunology and Immunogenetics Laboratory, Room no. 26, CCE Building, ACTREC, Sector -22, Kharghar, Navi Mumbai – 410210 Maharashtra, India
Email-id: tii.hla[at]actrec[dot]gov[dot]in
Staff
Staff
Sr. No.NameDesignation
1.Dr. Selma Z. D’SilvaScientific Officer C Officiating-Officer in Charge
2.Ms. Manisha TambeScientific Assistant E
3.Ms. Jyoti RajakScientific Assistant C
4.Ms. Alfiya FirfireScientific Assistant B
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