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Principal Investigator

Dr. Jyoti Anand Kode

Dr. Jyoti Anand Kode

Principal Investigator

Honors and Recognitions

  • Data Image was selected for special section ‘Science as Art” in NIH-FDA IIG NEWSLETTER November 2022. Jyoti Kode, Trupti Pradhan, Vaishali Kailaje. This is how phytochemical from dietary resource exerts innate immunity by regulating lung inflammasome. https://www.niaid.nih.gov/sites/default/files/iig-newsletter-nov-2022.pdf November 2022.
  • Subject expert for PhD topic approval for Mumbai University at NIIH, Parel, 23rd December, 2022.
  • Reviewer for SERB, Govt of India for CRG projects, December 2022.
  • Panel Member, Board of University Teaching & Research, Amity University of Biotechnology for selection of PhD Topic proposal, Panvel, 17th October, 2022.
  • Editorial Board Member, Cancer Biomarkers, IOS Press, The Netherlands. http://iospress.com/cancer-biomarkers 13th October, 2022; 2023-2025.
  • Member at International Union of Immunological Societies (IUIS) General Assembly, Berlin, nominated by National Board, Indian Immunology Society. Term 2022-25. 12th October, 2022
  • Recipient of SERB POWER Grant (Promoting Opportunities for Women in Exploratory Research), Government of India, May 2022-2025.....read more
  • Recipient of Bursary award from Immunology Foundation, New Delhi. Jyoti Kode, Jitendra Maharana, K. Nirmal Kumar, Trupti Pradhan, Arvind Ingle, Madan Barkume, Meena Patkar, Namitha Thampi, Ankita Patil, Anand Vaibhaw, Jeshma Kovvuri, Ahmed Kamal. (e-Poster Presentation). Phenstatin based indole linked chalcone compound 9a exhibits anti-oral cancer activity through regulating NLRP3 inflammasome pathway. 113th Annual Meeting of American Association of Cancer Research 2022 at New Orleans, Louisiana as e-poster. 8-13th April, 2022
  • Received “Certificate of Excellence in Reviewing” from Editorial Board of “Journal of Advances in Medicine and Medical Research” 1st March, 2022.
  • Invited Editorial Board Member, World Journal of Stem Cells, Baishideng Publishing Group Inc, California, USA for period 2022-2025. 23rd December, 2021.
  • Recognition as “Outstanding Editorial Board Member” and chosen as the cover person for the latest issue of World Journal of Stem Cells (WJSC) by Baishideng Publishing Group (BPG) Inc., USA, 17th May, 2021.
  • Invited Editorial Board Member, World Journal of Stem Cells, Baishideng Publishing Group Inc, California, USA, April 2018- December 2021; April, 2018.
  • Reflection image of “Titanium coated with nanocomposite and seeded with MG63” was shortlisted with good score (40th rank out of 700 images) for EMBO (European Molecular Biology Organization) Journal Cover Contest 2009, February, 2009.
  • ISSCR Travel Award: An emerging technology of Stem Cell and Chemokine therapy for cancer: Ex-vivo expansion of human CD34+ cells manipulated with a mixture of cytokines and Stromal Cell Derived Factor 1 at the 6th Annual Meeting of International Society for Stem Cell Research, Philadelphia, USA: June 10-14, 2008.
  • Recipient of ISSCR Travel Award, International Travel Fellowship from Department of Biotechnology, Government of India and Immunology Foundation, New Delhi to present paper titled ”Bone Tissue Engineering using Human Mesenchymal Stem Cells: Role of SDF1-CXCR4 axis (Poster Presentation): 5th Annual Meeting of International Society for Stem Cell Research, Cairns, Australia: June 17-20, 2007
  • Recipient of fellowship from British Society of Haematology Trust, Sir Dorabji Tata Trust and Pirozshah Godrej Foundation for presenting a paper entitled, “Selective migration of IgVH3+ B-cell chronic lymphocytic leukemia clones in response to chemokine SDF1” at the 46th Annual Scientific Meeting of British Society of Haematology, Edinburgh, UK. 3-5th April 2006.
  • Recipient of Best poster presentation of the paper entitled “Distinct IgVH genotype in B-CLL cells migrating against chemokine SDF1” at the 24th Annual Convention of Indian Association for Cancer Research, and International Symposium on HPV and cervical cancer at IPCO, Noida, February 9-12, 2005.
  • Recipient of VB Kamat award for the best podium presentation of the paper entitled “Clonal T-cell receptor γ and δ gene rearrangements in T-cell acute lymphoblastic leukemia at diagnosis: Predictor of prognosis and response to chemotherapy, Indian Association for Cancer Research, January 29th-31st 2004.
  • Best Poster Presentation Award: TCR gamma-delta gene rearrangements and cytotoxic function of lymphocytes in patients with T-cell acute lymphoblastic leukemia" in the 24th Annual conference of Indian Immunology Society, Calcutta, 22-24th December 1997.
  • Dr. L.D.Sanghvi Oral Presentation Award: Interleukin-12 augments cytotoxic potential of gamma-delta T cells from patients with Chronic Myelogenous leukemia" in the 21st Annual conference of Bombay Haematology Group, Tata Memorial Centre, 15-16th March 1997.
  • Recipient of Amgen Travel grant for Young Scientists: Poster presentation on paper titled, “Interleukin-12 augments cytotoxic potential of gamma-delta T cells from patients with Chronic Myelogenous Leukaemia” at the Second Meeting of European Haematology Association, Paris, France during May 29 to June 1,1996.
  • Recipient of R.D. Birla Smarak Kosh Fellowship, Sir Dorabji Tata Trust Fellowship and Sir Ratan Tata fund for presenting a paper entitled, "Killing of mycobacteria-infected macrophages by LAK cells from leprosy patients", at the XIV International Leprosy Congress, Orlando, Florida, USA and a visit to Dr. Peter Gregersen's laboratory, Northshore University Hospital, New York, USA to learn modern molecular immunological techniques on "Analysis of TCR Vβ CDR3 length restriction in population of CD4+ T cells". 1993.
  • Senior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Government of India. 1990 to 1992.
  • Received the Best Poster award for the paper entitled, "Recognition of ICRC, M.leprae and other mycobacterial antigens by sera from leprosy patients" at the XVII Annual Conference of Indian Immunology Society, Lucknow, 1990.
  • Department of Biotechnology (previously National Biotechnology Board) Fellowship for training as a part of M.Sc. Biotechnology Course in “Hybridoma Technology” at Immunology Division, Cancer Research Institute, Mumbai: May-June 1986.
  • Junior/senior Research Fellowship, CSIR, Government of India. 1988 to 1992.
  • Department of Biotechnology (previously National Biotechnology Board) Fellowship for studying M.Sc. 1985 to 1987.
  • Open Merit Scholarship, Government of India for studying B.Sc. 1982 to 1985.

Research Interests

  • Deciphering innate immune pathway involvement in various cancers
  • Understanding immune receptor repertoire, secretome and genomic landscape of immune cells in cancer patients on immune checkpoint blockade therapy
  • Evaluation of CD26-adenosine signaling axis in allogeneic transplant donors and recipients
  • Evaluation of soluble immune markers as prognostic biomarker for hematological and solid cancer
  • Understanding mesenchymal stem cells and leukemic blasts cross-talk in management of acute myeloid leukemia
  • Understanding mechanistic role of medicinal plant extracts in controlling leukemia growth
  • Exploring immunomodulatory properties and biomedical applications of natural extracts/ compounds

Event Conducted

Ongoing Research Projects

  • CD26

    CD26 and adenosine signaling pathway molecules as regulators of immune reconstitut…

    CD26 and adenosine signaling pathway molecules as regulators of immune reconstitution in… more

  • Proj3

    A study to evaluate the prognostic value of biomarkers in patients with Hodgkin…

    A study to evaluate the prognostic value of biomarkers in patients with Hodgkin’s Lympho… more

  • Proj 1

    Study of stem cell niche favoring immune evasion and maintenance of leukemia suppo…

    Study of stem cell niche favoring immune evasion and maintenance of leukemia supportive… more

  • Drug resistance in AML

    Understanding Drug Resistance in Acute Myeloid Leukemia: Role of Mesenchymal Stem…

    Understanding Drug Resistance in Acute Myeloid Leukemia: Role of Mesenchymal Stem Cells… more

  • project1

    Human tumor xenografts as in vivo testing model

    Human tumor xenografts as in vivo testing modelsmore

  • project1

    Screening of drugs for anti-cancer activity using in vivo animal models.

    Screening of drugs for anti-cancer activity using in vivo animal models.… more

  • project1

    A phase II trial to study of efficacy, toxicity and immunomodulatory effect of Car…

    A phase II trial to study of efficacy, toxicity and immunomodulatory effect of Carctol-S… more

  • AgNP

    Understanding mechanistic role of seaweed nanocomposite formulation FK-94-1 and me…

    Understanding mechanistic role of seaweed nanocomposite formulation FK-94-1 and medicinal plant extract FK-59-5… more

Lab Members

पूर्व छात्र

PUBLICATIONS

Contact

Office Contact

Dr. Jyoti Anand Kode

Kode Lab, Advance Centre for Treatment Research & Education in Cancer, Tata Memorial Centre, (ACTREC), Plot No. 1 & 2, Sector 22, Kharghar, Navi Mumbai-410210. Maharashtra India.+91 (022) 2740 5000/ 6873 5000 Extn-5030 jkode@actrec.gov.in

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