Science Sparks @ ACTREC

Publications
- 1. Chaudhary N, Mandal D, Choudhary B, Patra S, Jain D, Poonia P, Shaikh S, Tekalkar S, Malvankar S, Shivashankar A, Jog E, Pilankar L, Thorat R, Kailje V, Khanna S, Manna S, Khan B, Jadhav A, Sharma K, Ramu S, Sahoo S, Jolly MK, Dalal SN, Sinha S, Nair N, Ruppin E, Lamballe F, Maina F, Verma N (2025).Low-GPX4 drives a sustained drug-tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation. Redox Biology.
- 2. Rajput NH (2025). The digital shift in oncology EMRs in LMICs. ESMO Real World Data and Digital Oncology. 10:100183.
- 3. Bagdiya P, Soni N, Jaiswal D, Dalvi S, Kanitkar T, Madhusudhan MS, Venkatraman P (2025). ATP-driven allosteric regulation of 14-3-3: positive modulation of ATP hydrolysis and negative regulation of peptide binding. FASEB Journal.39(18):e70985.
- 4. Keshari R, Bagale R, Rath S, Raut S, Bhatt LK, De A, Sen S, Srivastava R (2025). Soya lecithin–PLGA based hybrid nanocomposite enhances resveratrol delivery for psoriasis treatment and management. Industrial Crops and Products.236:121575.
Patent
Kode J, Mathen C (2025). Immune modulating therapy using UC-MSC-CM to inhibit tumor growth. (Indian Patent Number: 570565)

Video of the Week
Restoring the Core Logic of Randomization to Avert Common Pitfalls in Biopharmaceutical Statistics
Upcoming Events
November 20-22, 2025
At ACTREC, Tata Memorial Centre, Kharghar
November 12-14, 2025
At ACTREC, Tata Memorial Centre, Kharghar
Do You Know?
In 2012, Vismodegib (Erivedge) was the first drug approved for basal cell carcinoma, the most common type of skin cancer.

Cancer News
Eurekalert, 10/09/2025
While this research highlights the role mitochondrial DNA mutations might play in leukemia, the main achievement is the creation of a novel multidimensional approach to investigate mtDNA. Kundu is optimistic about the value of digging deeper into this overlooked feature of cancer growth...
Sciencedaily, 11/09/2025
Researchers discovered that cutting off blood flow accelerates cancer growth by prematurely aging the bone marrow and weakening the immune system. In mouse models, restricted blood flow doubled the growth rate of breast tumors, mimicking changes seen during aging...
News-Medical, 11/09/2025
The study sheds light on a newly discovered molecular interaction that drives rapid migration of dendritic cells, a type of immune cell that capture pathogens. Migrating dendritic cells need to exert backward forces onto the environment to propel themselves forward. In addition,...
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